Farkhutdinov U R
Ter Arkh. 2007;79(3):44-8.
To investigate action of intravascular laser blood irradiation (ILBI) on production of active oxygen forms (AOF) in patients with bronchial asthma (BA).
The trial included 59 BA patients aged 20 to 60 years (mean age 40.2 +/- 3.1 years). AOF generation in whole blood was registered with luminol-dependent chemiluminescence (CL). Basic therapy was given to 42 patients. ILBI was added to basic therapy in 17 patients.
. CL of whole blood in BA patients depended on severity of inflammation. BA patients with intensive CL exposed to ILBI retained free radical oxidation defects and the disease symptoms. In low intensity of blood CL, ILBI activated A OF generation and raised treatment effectiveness.
ILBI raises AOF production in the whole blood of BA patients. CL registration can be used for validation of ILBI administration in BA patients and control of effectiveness of laser therapy.
研究血管内激光照射血液（ILBI）对支气管哮喘（BA）患者活性氧形式（AOF）产生的作用。
该试验纳入了59例年龄在20至60岁（平均年龄40.2±3.1岁）的BA患者。采用鲁米诺依赖性化学发光（CL）法记录全血中AOF的生成情况。42例患者接受基础治疗，17例患者在基础治疗的基础上加用ILBI。
BA患者全血的CL取决于炎症的严重程度。CL强度高的BA患者接受ILBI治疗后，自由基氧化缺陷和疾病症状依然存在。血液CL强度低时，ILBI可激活AOF的生成并提高治疗效果。
ILBI可提高BA患者全血中AOF的产生。CL记录可用于验证BA患者ILBI治疗的适用性及控制激光治疗的效果。
