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支气管哮喘患者治疗中有效的低强度激光疗法(文献综述)

Methods of effective low-level laser therapy in the treatment of patients with bronchial asthma (literature review).

作者信息

Moskvin Sergey Vladimirovich, Khadartsev Aleksandr Agubechirovich

机构信息

O.K. Skobelkin State Scientific Center of Laser Medicine under the Federal Medical Biological Agency, Moscow, 121165, Russia.

Medical Institute, Tula State University, Tula, 300028, Russia.

出版信息

Biomedicine (Taipei). 2020 Mar 28;10(1):1-20. doi: 10.37796/2211-8039.1000. eCollection 2020.

DOI:10.37796/2211-8039.1000
PMID:33854908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7608842/
Abstract

Bronchial asthma is an autoimmune disease, one of the most common and practically non-treatable by standard methods. At present, the used drugs only maintain a state of temporary remission, simultaneously having a negative effect on various organs and structures and causing side effects. At the same time, the experts have ignored more than 50 years of successful experience of low-level laser therapy, the results of hundreds of studies proving the effectiveness of the method in treating patients with all forms of bronchial asthma. It is proved that therapeutic and periodic (2-4 per year) courses of low-level laser therapy can significantly decrease the frequency and severity of attacks, reduce or cancel the reception of medicines, as well as negative consequences. In this brief review, only some part of studies is given as an example; pediatrics issues are almost not discussed. However, the review clearly demonstrates that various methods of laser illumination (specific techniques are given) make it possible to influence almost all the known pathogenesis of the disease, and low-level laser therapy is a truly effective method of treatment. We note that there are very few publications published on the topic outside of Russia. Russian scientists, as always, are ahead of world science and low-level laser therapy practice.

摘要

支气管哮喘是一种自身免疫性疾病,是最常见且几乎无法用标准方法治疗的疾病之一。目前,所使用的药物仅能维持暂时缓解状态,同时对各种器官和结构产生负面影响并引发副作用。与此同时,专家们忽视了低强度激光疗法50多年来的成功经验,数百项研究结果证明该方法对治疗各种形式的支气管哮喘患者有效。事实证明,低强度激光疗法的治疗性和周期性(每年2 - 4次)疗程可显著降低发作频率和严重程度,减少或停用药物以及消除负面后果。在这篇简短的综述中,仅列举了部分研究作为示例;几乎未讨论儿科问题。然而,该综述清楚地表明,各种激光照射方法(给出了具体技术)能够影响几乎所有已知的疾病发病机制,低强度激光疗法是一种真正有效的治疗方法。我们注意到,俄罗斯境外关于该主题的出版物极少。一如既往,俄罗斯科学家在世界科学和低强度激光疗法实践方面领先。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e57/7608842/15bd5e33b946/bmed-10-01-001f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e57/7608842/7eaf061bf571/bmed-10-01-001f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e57/7608842/15bd5e33b946/bmed-10-01-001f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e57/7608842/7eaf061bf571/bmed-10-01-001f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e57/7608842/15bd5e33b946/bmed-10-01-001f2.jpg

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本文引用的文献

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[The commonest therapeutic methods for laser irradiation of blood].[激光照射血液的最常见治疗方法]
Vopr Kurortol Fizioter Lech Fiz Kult. 2017 Dec 5;94(5):10-17. doi: 10.17116/kurort201794510-17.
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Only lasers can be used for low level laser therapy.仅激光可用于低强度激光治疗。
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光生物调节治疗慢性肾脏病的潜力。
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Low-Level Laser Therapy in Prevention of the Development of Endothelial Dysfunction and Clinical Experience of Treatment and Rehabilitation of COVID-19 Patients.低强度激光疗法预防内皮功能障碍的发生及COVID-19患者治疗与康复的临床经验
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Vopr Kurortol Fizioter Lech Fiz Kult. 2017;94(4):14-18. doi: 10.17116/kurort201794414-18.
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Diagnosis and Management of Asthma in Adults: A Review.成人哮喘的诊断与管理:综述。
JAMA. 2017 Jul 18;318(3):279-290. doi: 10.1001/jama.2017.8372.
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Evaluation of the improvement effect of laser acupuncture biostimulation in asthmatic children by exhaled inflammatory biomarker level of nitric oxide.通过呼出一氧化氮炎症生物标志物水平评估激光针刺生物刺激对哮喘儿童的改善效果。
Lasers Med Sci. 2017 Jan;32(1):53-59. doi: 10.1007/s10103-016-2082-9. Epub 2016 Oct 5.
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The chemokines secretion and the oxidative stress are targets of low-level laser therapy in allergic lung inflammation.趋化因子分泌和氧化应激是过敏性肺部炎症中低强度激光治疗的靶点。
J Biophotonics. 2016 Dec;9(11-12):1208-1221. doi: 10.1002/jbio.201600061. Epub 2016 Sep 20.
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Low-level laser therapy inhibits bronchoconstriction, Th2 inflammation and airway remodeling in allergic asthma.低强度激光疗法可抑制过敏性哮喘中的支气管收缩、Th2炎症和气道重塑。
Respir Physiol Neurobiol. 2014 Apr 1;194:37-48. doi: 10.1016/j.resp.2014.01.008. Epub 2014 Jan 28.
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Low-level laser therapy suppresses the oxidative stress-induced glucocorticoids resistance in U937 cells: relevance to cytokine secretion and histone deacetylase in alveolar macrophages.低水平激光疗法抑制 U937 细胞中氧化应激诱导的糖皮质激素抵抗:与肺泡巨噬细胞中细胞因子分泌和组蛋白去乙酰化酶的相关性。
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