Boronikhina T V, Iatskovskiĭ A N
Morfologiia. 2007;131(1):63-7.
Bulbourethral gland glycoprotein (GP) composition was studied histochemically in men of different age groups (varying from neonatal period up to 90 years). No less than 5 cases were examined for each age group. In children and juveniles, neutral GP prevailed in the glandular cells, the proportion of neutral GP gradually decreasing with puberty. In youths and in men of mature age, acid GP became the predominant component of glandular secretion. In elderly and senescent men the ratio of acid and neutral GP again was found to change in favor of the latter. In all the age groups, acid GP were represented mainly by sialomucins, both sialidase-labile and sialidase-resistant. In the glands of men aged 17 years and older, sulphomucins were also detected; the intensity of their synthesis increased from the youth to the elderly period and decreased in senescent persons. Functional significance of different types of GP in the secretion of bulbourethral glands is discussed as well as the possible hormonal machanisms of their synthesis.
采用组织化学方法研究了不同年龄组（从新生儿期到90岁）男性的球尿道腺糖蛋白（GP）组成。每个年龄组检查不少于5例。在儿童和青少年中，中性GP在腺细胞中占主导地位，随着青春期的到来，中性GP的比例逐渐降低。在青年人和成年男性中，酸性GP成为腺分泌的主要成分。在老年男性中，酸性和中性GP的比例再次发生变化，有利于后者。在所有年龄组中，酸性GP主要由唾液酸黏液素代表，包括对唾液酸酶敏感和不敏感的。在17岁及以上男性的腺体中也检测到了硫酸黏液素；其合成强度从青年期到老年期增加，在衰老个体中降低。讨论了不同类型GP在球尿道腺分泌中的功能意义以及它们合成的可能激素机制。
