Collantes E, Zarco P, Muñoz E, Juanola X, Mulero J, Fernández-Sueiro J L, Torre-Alonso J C, Gratacós J, González C, Batlle E, Fernández P, Linares L F, Brito E, Carmona L
Department of Rheumatology, Hospital Reina Sofia and University of Córdoba, Córdoba, Spain.
Rheumatology (Oxford). 2007 Aug;46(8):1309-15. doi: 10.1093/rheumatology/kem084. Epub 2007 May 27.
The national registry of spondyloarthropathies (REGISPONSER) is launched to classify patients with this group of diseases treated in Spanish rheumatology clinics. This manuscript describes the methodological and organizational background as well as characteristics of patients finally included, and provides a comparative analysis between characteristics of both ankylosing spondylitis and undifferentiated spondyloarthropathy groups of patients.
Twelve members of the GRESSER group have participated in the registry, for a one-year recruitment period. All consecutively registered adult patients treated in their clinics met the classification criteria of the European Spondyloarthropathies Study Group (ESSG). Data collected reflect the socio-demographic characteristics, as well as disease activity and functional status, clinical form at onset, treatment used and quality of life; all measured by standard instruments.
Throughout 1 yr, 1385 patients have been included in the registry: 939 males (68%) and 440 females (32%), with an average age of 47 +/- 13 years (mean +/- s.d.), and an average disease duration of 12 +/- 9 years. Diagnoses of the included patients were: AS (n = 842, 61%), PsA (n = 290, 21%), u-SpA (n = 205, 15%), reactive arthritis (n = 16, 1.2%), inflammatory bowel disease arthritis (n = 13, 0.9%) and JCA-spondyloathropathy (n = 13, 0.9%). Regarding clinical form, 54% had axial disease, 20% peripheral disease, 24% mixed disease and 0.6% isolated enthesitic form. Low-back pain was the first symptom reported in 53% of the patients, and most common extra-articular disease manifestations were psoriasis (25%), anterior uveitis (16%) and intestinal inflammatory disease (4%). Some kind of work disability was reported by 353 patients (25.5%).
Such databases are very useful to obtain information about characteristics of SpA patients treated in a certain location or following a specific treatment practice, and provide a tool for assessing the impact of the disease. Data collected in this registry provide an appropriate clinical and demographic profile of patients suffering from SpA in Spain.
启动脊柱关节病国家注册系统（REGISPONSER），对在西班牙风湿病诊所接受治疗的这类疾病患者进行分类。本手稿描述了方法学和组织背景以及最终纳入患者的特征，并对强直性脊柱炎和未分化脊柱关节病两组患者的特征进行了比较分析。
GRESSER组的12名成员参与了该注册系统，招募期为一年。在其诊所接受治疗的所有连续登记的成年患者均符合欧洲脊柱关节病研究组（ESSG）的分类标准。收集的数据反映了社会人口学特征、疾病活动度和功能状态、发病时的临床类型、所用治疗方法和生活质量；所有这些均通过标准仪器进行测量。
在1年的时间里，共有1385名患者被纳入该注册系统：男性939名（68%），女性440名（32%），平均年龄为47±13岁（均值±标准差），平均病程为12±9年。纳入患者的诊断结果为：强直性脊柱炎（n = 842，61%）、银屑病关节炎（n = 290，21%）、未分化脊柱关节病（n = 205，15%）、反应性关节炎（n = 16，1.2%）、炎症性肠病关节炎（n = 13，0.9%）和幼年型慢性关节炎-脊柱关节病（n = 13，0.9%）。关于临床类型，54%为中轴型疾病，20%为外周型疾病，24%为混合型疾病，0.6%为孤立性附着点炎型。53%的患者报告的首发症状为下背痛，最常见的关节外疾病表现为银屑病（25%）、前葡萄膜炎（16%）和肠道炎症性疾病（4%）。353名患者（25.5%）报告有某种工作能力丧失。
这样的数据库对于获取在特定地点接受治疗或遵循特定治疗方案的脊柱关节病患者的特征信息非常有用，并为评估疾病的影响提供了一个工具。该注册系统收集的数据提供了西班牙脊柱关节病患者合适的临床和人口统计学概况。
