Yaris Nilgun, Cakir Murat, Kalyoncu Mukaddes, Okten Aysenur
Department of Pediatric Oncology, Faculty of Medicine, Trabzon, Turkey.
Indian J Pediatr. 2007 May;74(5):505-6. doi: 10.1007/s12098-007-0089-8.
Hyperpigmentation is one of the cutaneous side effects of chemotherapautic agents, but it is usually accepted as a cosmetic problem. We report a child with yolk sac tumor who developed localized pigmentation after the first course of chemotherapy regimen that included cisplatin, etoposide and bleomycin. The hyperpigmentation was diffuse scattered, flagellate like and linear streaking which was thought to be mainly related to the skin toxicity of bleomycin.
色素沉着是化疗药物的皮肤副作用之一，但通常被认为是一个美容问题。我们报告一名患有卵黄囊瘤的儿童，在接受包括顺铂、依托泊苷和博来霉素的第一个化疗疗程后出现了局部色素沉着。色素沉着呈弥漫性散在、鞭毛状和线状条纹，被认为主要与博来霉素的皮肤毒性有关。
