Susser W S, Whitaker-Worth D L, Grant-Kels J M
Department of Dermatology, University of Connecticut School of Medicine, Farmington, USA.
J Am Acad Dermatol. 1999 Mar;40(3):367-98; quiz 399-400. doi: 10.1016/s0190-9622(99)70488-3.
Chemotherapeutic agents are a widely used treatment modality. Side effects range from common to unusual and may be confused with other cutaneous sequelae of oncologic treatment. The goal of this communication is to elaborate on previous descriptions of the cutaneous manifestations of chemotherapeutic treatment and to discuss more recent findings.
At the conclusion of this learning activity, participants should be able to generate a differential diagnosis of possible etiologies for varying patterns of cutaneous involvement in patients receiving chemotherapy and identify the various cutaneous side effects of chemotherapeutic treatment. In addition, they should be able to distinguish life-threatening side effects that require immediate management from more benign manifestations of chemotherapeutic treatment.
化疗药物是一种广泛使用的治疗方式。其副作用从常见到不常见不等,可能会与肿瘤治疗的其他皮肤后遗症相混淆。本文的目的是详细阐述化疗治疗皮肤表现的既往描述,并讨论最新发现。
在本学习活动结束时,参与者应能够对接受化疗患者不同皮肤受累模式的可能病因进行鉴别诊断,并识别化疗治疗的各种皮肤副作用。此外,他们应能够区分需要立即处理的危及生命的副作用与化疗治疗的较良性表现。