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[人体测量学指标作为日本社区居住老年人死亡率的预测因素:名古屋体弱老年人纵向研究(NLS-FE)]

[Anthropometric measurements as a predictor of mortality of community-dwelling Japanese elderly: the Nagoya Longitudinal Study of Frail Elderly (NLS-FE)].

作者信息

Enoki Hiromi, Kuzuya Masafumi, Masuda Yuichiro, Hirakawa Yoshihisa, Iwata Mitsunaga, Izawa Sachiko, Hasegawa Jun, Iguchi Akihisa

机构信息

Department of Geriatrics, Nagoya University Graduate School of Medicine.

出版信息

Nihon Ronen Igakkai Zasshi. 2007 Mar;44(2):212-8. doi: 10.3143/geriatrics.44.212.

Abstract

AIM

This study aimed to evaluate the relationship between anthropometric measurements and mortality among community-dwelling frail elderly.

METHODS

This study was a prospective cohort analysis of 520 community-dwelling elderly registered in the Nagoya Longitudinal Study for Frail Elderly (NLS-FE). Data included the participants' demographic characteristics, body mass index (BMI), mid-arm circumference (MAC), triceps skinfold (TSF), and arm muscle area (AMA), basic activities of daily living, comorbidity. BMI and TSF values were categorized into three groups, respectively, according to above the 75th percentile, the 25-75th percentile, and below the 25th percentile of Japanese Anthropometric Reference Data (JARD 2001). Survival analysis of 21-month mortality was conducted using Kaplan-Meier curves and multivariate Cox proportional hazards models.

RESULTS

BMI and TSF were independent risk factors for 21-month mortality in the study participants. Significant higher risk of 21-month mortality was observed in participants below the 75th percentile of BMI or below the 25th percentile of TSF set in JARD 2001. A striking increase in the risk of 21-month mortality, adjusting for potential confounding factors, was observed in the below 75th percentile of the BMI group with a below 25th percentile TSF of JARD 2001, compared with the 75th or above percentile BMI group with the 25th or above percentile TSF.

CONCLUSION

The combination of BMI and TSF is a predictor of 21-month mortality among older people with ADL dysfunction.

摘要

目的

本研究旨在评估社区居住的体弱老年人的人体测量指标与死亡率之间的关系。

方法

本研究是对名古屋体弱老年人纵向研究(NLS-FE)中登记的520名社区居住老年人进行的前瞻性队列分析。数据包括参与者的人口统计学特征、体重指数(BMI)、上臂围(MAC)、三头肌皮褶厚度(TSF)和上臂肌肉面积(AMA)、日常生活基本活动能力、合并症。根据日本人体测量参考数据(JARD 2001)的第75百分位数以上、第25至75百分位数以及第25百分位数以下,将BMI和TSF值分别分为三组。使用Kaplan-Meier曲线和多变量Cox比例风险模型对21个月死亡率进行生存分析。

结果

BMI和TSF是研究参与者21个月死亡率的独立危险因素。在BMI低于JARD 2001设定的第75百分位数或TSF低于第25百分位数的参与者中,观察到21个月死亡率的风险显著更高。在调整潜在混杂因素后,与BMI处于第75百分位数或以上且TSF处于第25百分位数或以上的组相比,BMI处于第75百分位数以下且TSF处于JARD 2001第25百分位数以下的组中,21个月死亡率的风险显著增加。

结论

BMI和TSF的组合是日常生活活动功能障碍老年人21个月死亡率的预测指标。

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