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听觉系统的成熟:1. 瞬态耳声发射作为内耳成熟的指标。

Maturation of the auditory system: 1. Transient otoacoustic emissions as an index of inner ear maturation.

作者信息

Gkoritsa Eleni, Korres Stavros, Psarommatis Ioannis, Tsakanikos Michael, Apostolopoulos Nikolaos, Ferekidis Eleftherios

机构信息

1st Department of Otorhinolaryngology, University of Athens, Hippokration Hospital of Athens, Greece.

出版信息

Int J Audiol. 2007 Jun;46(6):271-6. doi: 10.1080/14992020701261397.

DOI:10.1080/14992020701261397
PMID:17530511
Abstract

The transiently evoked otoacoustic emission amplitude of 42 preterm babies (84 ears; post-conceptional age [PCA] 30-36 weeks) was compared with the TEOAE amplitude of 39 full-term babies (78 ears; PCA 37-45 weeks) in order to trace the inner ear maturation characteristics. An ILO-92 otoacoustic emission recording system was used with linear clicks of 70 dB peak equivalent SPL. The results obtained indicated: (1) There was no statistically significant difference between preterm and full-term ears; (2) There was no significant difference between males and females; (3) There was a significant difference between left and right ear TEOAE amplitude; (4) The interaction of ear with age in relation to TEOAE amplitude was statistically significant; (5) Noise and stimulus parameters did not reveal any significant differences between right and left ears; (6) A positive correlation existed between birthweight and TEOAE amplitude; and (7) A negative correlation existed between aminoglycoside treatment and TEOAE amplitude. The results indicate subtle changes in TEOAE amplitude over time, showing a natural development of the inner ear function during the process of maturation.

摘要

为了探寻内耳成熟特征,比较了42名早产儿(84耳;孕龄[PCA]30 - 36周)的瞬态诱发耳声发射幅度与39名足月儿(78耳;PCA 37 - 45周)的TEOAE幅度。使用ILO - 92耳声发射记录系统,采用峰值等效声压级为70 dB的线性短声。获得的结果表明:(1)早产儿耳和足月儿耳之间无统计学显著差异;(2)男性和女性之间无显著差异;(3)左耳和右耳的TEOAE幅度存在显著差异;(4)耳与年龄在TEOAE幅度方面的交互作用具有统计学显著性;(5)噪声和刺激参数在右耳和左耳之间未显示出任何显著差异;(6)出生体重与TEOAE幅度呈正相关;(7)氨基糖苷类药物治疗与TEOAE幅度呈负相关。结果表明TEOAE幅度随时间有细微变化,显示出内耳功能在成熟过程中的自然发育。

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