Gkoritsa Eleni, Korres Stavros, Segas Ioannis, Xenelis Ioannis, Apostolopoulos Nikolaos, Ferekidis Eleftherios
1st Department of Otorhinolaryngology, University of Athens, Hippokration Hospital of Athens, Greece.
Int J Audiol. 2007 Jun;46(6):277-86. doi: 10.1080/14992020701261405.
Contralateral suppression of transient otoacoustic emissions in 42 premature babies (84 ears; post-conceptional age [PCA] 30-36 weeks) was compared to that of 39 full-term babies (78 ears; PCA: 37-45 weeks). Eighteen healthy adults and ten young children (5-14 years old) were studied as controls. Risk factors for hearing loss were registered in both preterm and full-term groups. An ILO-92 otoacoustic emission recording system was used to deliver linear clicks to the ear examined and broadband noise to the contralateral ear in an alternating on and off mode. Suppression in full-term babies was statistically higher than in preterms, whereas no differences existed between children and adults and children and full-terms. Peripheral auditory lateralization was evident in adults but was observed only as a trend in newborns. Only prematurity at the time of examination and aminoglycoside treatment for more than seven days had a negative impact on suppression. The results support the conclusion that maturation of the efferent system takes place from 30 to 45 weeks PCA. The exact age at which this maturation is accomplished has not yet been clearly determined.
对42名早产儿（84只耳；孕龄[PCA]30 - 36周）的瞬态耳声发射的对侧抑制情况与39名足月儿（78只耳；PCA：37 - 45周）进行了比较。选取18名健康成年人及10名儿童（5 - 14岁）作为对照进行研究。在早产组和足月组中均记录了听力损失的风险因素。使用ILO - 92耳声发射记录系统，以交替开和关的模式向受试耳发送线性短声，并向对侧耳发送宽带噪声。足月儿的抑制在统计学上高于早产儿，而儿童与成年人以及儿童与足月儿之间无差异。外周听觉定位在成年人中明显，但在新生儿中仅表现为一种趋势。仅检查时的早产和超过7天的氨基糖苷类药物治疗对抑制有负面影响。结果支持这样的结论，即传出系统的成熟发生在PCA 30至45周之间。这种成熟完成的确切年龄尚未明确确定。
