Universidade Federal do Rio de Janeiro - UFRJ - Rio de Janeiro (RJ), Brasil.
Instituto Nacional de Educação de Surdos - INES - Rio de Janeiro (RJ), Brasil.
Codas. 2021 Oct 29;34(1):e20200300. doi: 10.1590/2317-1782/20212020300. eCollection 2021.
The goal of this study is to investigate the efferent auditory pathways inhibition in Turner's syndrome and to relate it to the cytogenetic profile.
This is a cross-sectional study with a comparison group. A sample with 94 participants divided into two groups: The study group was a sample of 40 patients diagnosed with Turner's syndrome (17.6 years of age). The control group was composed of 54 volunteers (18.9 years of age), female, without syndrome. The selected individuals were submitted to efferent auditory pathways inhibition research.
The mean of the inhibitory effect of the efferent auditory pathway in the study group in the right ear was 0.4 dB and in the comparison group it was 1.9 dB, however in the left ear the mean of the inhibitory effect of the efferent auditory pathway was 1.4 dB in the study group and 0.8 dB in the comparison group. The inhibitory effect of the efferent auditory pathway was present in 14 individuals with monosomy and in 15 with other cytogenetic alterations.
In the study group, the efferent auditory pathways inhibition value was significantly higher in the left ear and significantly lower than the control group in the right ear. There was no significant difference in efferent auditory pathways inhibition of right ear and left ear between the karyotype types.
本研究旨在探讨特纳综合征患者的传出听觉通路抑制情况，并将其与细胞遗传学特征相关联。
这是一项横断面研究，设有对照组。样本包括 94 名参与者，分为两组：研究组为 40 名确诊为特纳综合征的患者（17.6 岁）。对照组由 54 名志愿者（18.9 岁）组成，均为女性，无综合征。选择的个体接受传出听觉通路抑制研究。
研究组右耳传出听觉通路抑制效应的平均值为 0.4dB，对照组为 1.9dB；而研究组左耳传出听觉通路抑制效应的平均值为 1.4dB，对照组为 0.8dB。在单纯单体性和其他细胞遗传学改变的 14 例个体中存在传出听觉通路抑制效应。
在研究组中，左耳的传出听觉通路抑制值明显较高，而右耳的抑制值明显低于对照组。不同核型类型的右耳和左耳传出听觉通路抑制值之间无显著差异。
