Jones Deborah P, Camargo Carlos A, Speizer Frank E, Barr R Graham
Division of General Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.
J Asthma. 2007 May;44(4):291-5. doi: 10.1080/02770900701344116.
The authors tested the hypothesis that short stature predicts adult-onset asthma independent of obesity among women in the Nurses' Health Study. Height, weight, and physician-diagnosed asthma were assessed with validated questionnaire items. Proportional hazard models adjusted separately for weight and body mass index. The rate of newly diagnosed asthma was 1.55 times greater in the shortest versus the tallest quintile after adjustment for weight (95% CI, 1.26-1.91). After adjustment for body mass index, the rate ratio was 1.16 (95% CI, 0.94-1.42). Short stature predicted adult-onset asthma in a large cohort of women, but this association was not independent of obesity.
在护士健康研究中，作者检验了这样一个假设：在女性中，身材矮小独立于肥胖因素可预测成年后发生的哮喘。通过经过验证的问卷调查项目对身高、体重和医生诊断的哮喘进行评估。分别对体重和体重指数进行比例风险模型调整。在对体重进行调整后，最矮五分位数组新诊断哮喘的发生率是最高五分位数组的1.55倍（95%置信区间，1.26 - 1.91）。在对体重指数进行调整后，发生率比值为1.16（95%置信区间，0.94 - 1.42）。身材矮小在一大群女性中可预测成年后发生的哮喘，但这种关联并非独立于肥胖因素。
