种族主义经历与黑人女性健康研究中成年哮喘发病的关系。
Experiences of racism and the incidence of adult-onset asthma in the Black Women's Health Study.
机构信息
Slone Epidemiology Center at Boston University, Boston University, Boston, MA.
Slone Epidemiology Center at Boston University, Boston University, Boston, MA.
出版信息
Chest. 2014 Mar 1;145(3):480-485. doi: 10.1378/chest.13-0665.
BACKGROUND
Chronic stress resulting from experiences of racism may increase the incidence of adult-onset asthma through effects on the immune system and the airways. We conducted prospective analyses of the relation of experiences of racism with asthma incidence in the Black Women's Health Study, a prospective cohort of black women in the United States followed since 1995 with mailed biennial questionnaires.
METHODS
Among 38,142 participants followed from 1997 to 2011, 1,068 reported incident asthma. An everyday racism score was created based on five questions asked in 1997 and 2009 about the frequency in daily life of experiences of racism (eg, poor service in stores), and a lifetime racism score was based on questions about racism on the job, in housing, and by police. We used Cox regression models to derive multivariable incidence rate ratios (IRRs) and 95% CIs for categories of each racism score in relation to incident asthma.
RESULTS
The IRRs were 1.45 (95% CI, 1.19-1.78) for the highest compared with the lowest quartile of the 1997 everyday racism score (P for trend<.0001) and 1.44 (95% CI, 1.18-1.75) for the highest compared with the lowest category of 1997 lifetime racism. Among women who reported the same levels of racism in 1997 and 2009, the IRRs for the highest categories of everyday and lifetime racism were 2.12 (95% CI, 1.55-2.91) and 1.66 (95% CI, 1.20-2.30), respectively.
CONCLUSIONS
Given the high prevalence of experiences of racism and asthma in black women in the United States, a positive association between racism and asthma is of public health importance.
背景
由于种族主义经历而导致的慢性压力可能会通过对免疫系统和气道的影响，增加成年人哮喘的发病率。我们在美国进行了一项前瞻性分析，研究了种族主义经历与黑人女性健康研究中哮喘发病率的关系，该研究是一项针对美国黑人女性的前瞻性队列研究，自 1995 年以来通过邮寄两年一次的问卷进行随访。
方法
在 1997 年至 2011 年期间随访的 38142 名参与者中，有 1068 人报告了哮喘发作。根据 1997 年和 2009 年提出的五个问题，创建了一个日常种族主义评分，这些问题涉及日常生活中种族主义经历的频率（例如，在商店中受到的服务不佳），一个终身种族主义评分是基于关于工作、住房和警察中的种族主义问题的问题。我们使用 Cox 回归模型，得出每个种族主义评分类别与哮喘发作的多变量发病率比（IRR）和 95%置信区间（CI）。
结果
与最低四分位数相比，1997 年日常种族主义评分最高四分位数的 IRR 为 1.45（95%CI，1.19-1.78）（趋势 P<.0001），与 1997 年终身种族主义评分最低类别相比，最高类别为 1.44（95%CI，1.18-1.75）。在 1997 年和 2009 年均报告相同水平种族主义的女性中，日常和终身种族主义评分最高类别的 IRR 分别为 2.12（95%CI，1.55-2.91）和 1.66（95%CI，1.20-2.30）。
结论
鉴于美国黑人女性中种族主义和哮喘的高患病率，种族主义与哮喘之间的正相关关系具有公共卫生重要性。
Zotero 插件