Liu Yi, Klivansky Liana M, Khan Saeed I, Zhang Xiyun
The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.
Org Lett. 2007 Jun 21;9(13):2577-80. doi: 10.1021/ol070970s. Epub 2007 May 27.
Desymmetrized [2]catenanes were synthesized and shown to exhibit excellent translational selectivity. The templated synthesis takes effect from the formation of pseudorotaxanes between pi-rich crown ethers and a pi-deficient pyromellitic (PmI) unit, followed by macrocyclization around the crown ethers with the creation of a bipyridinium (BPy) unit. The crown ethers preferably encircle the BPy unit in the resulting [2]catenanes in both solution and the solid state, as indicated by various spectroscopic analyses.
合成了去对称化的[2]索烃，并证明其具有优异的平移选择性。模板合成从富π冠醚与贫π均苯四甲酸（PmI）单元之间形成准轮烷开始，随后围绕冠醚进行大环化，并生成联吡啶鎓（BPy）单元。各种光谱分析表明，在所得的[2]索烃中，冠醚在溶液和固态下均优先环绕BPy单元。
