Reicker Lindsay I, Tombaugh Tom N, Walker Lisa, Freedman Mark S
Psychology Department, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario, Canada.
Arch Clin Neuropsychol. 2007 Jun;22(5):655-64. doi: 10.1016/j.acn.2007.04.008. Epub 2007 May 25.
The ability of a newly developed measure of information processing to detect deficits in cognitive functioning associated with multiple sclerosis (MS) was investigated. The Computerized Tests of Information Processing (CTIP; Tombaugh, T., & Rees, L. (1999). Computerized Tests of Information Processing (CTIP). Unpublished test. Ottawa, Ontario, Canada: Carleton University) was administered to 60 clinically definite MS patients and 60 healthy controls. MS patients responded significantly slower than controls on the reaction time tests composing the CTIP. Moreover, as the CTIP tests became more difficult (i.e. as processing demands increased), the difference between the performances of the two groups progressively increased. These results suggest the CTIP is sensitive to the cognitive deficits observed in MS and that this measure has the potential to serve as a viable alternative to traditional measures of information processing speed currently in use with MS patients.
研究了一种新开发的信息处理测量方法检测与多发性硬化症（MS）相关的认知功能缺陷的能力。对60名临床确诊的MS患者和60名健康对照者进行了信息处理计算机化测试（CTIP；Tombaugh，T.，& Rees，L.（1999年）。信息处理计算机化测试（CTIP）。未发表的测试。加拿大安大略省渥太华：卡尔顿大学）。在构成CTIP的反应时间测试中，MS患者的反应明显比对照组慢。此外，随着CTIP测试变得更加困难（即随着处理需求增加），两组表现之间的差异逐渐增大。这些结果表明，CTIP对MS中观察到的认知缺陷敏感，并且该测量方法有可能成为目前用于MS患者的传统信息处理速度测量方法的可行替代方案。
