Deshpande Ranjit P, Casselman Filip, Bakir Ihsan, Cammu Guy, Wellens Francis, De Geest Raphael, Degrieck Ivan, Van Praet Frank, Vermeulen Yvette, Vanermen Hugo
Department of Cardiovascular and Thoracic Surgery, OLV Clinic, Aalst, Belgium.
Ann Thorac Surg. 2007 Jun;83(6):2142-6. doi: 10.1016/j.athoracsur.2007.01.064.
The purpose of this study is to report our 9 years' experience with endoscopic cardiac tumor resection using the port access approach.
From March 1997 to December 2005, 27 patients (mean age, 56.2 +/- 16.9 years; 70% female) underwent endoscopic cardiac tumor resection using endocardiopulmonary bypass and endoaortic-balloon clamp technique. Nineteen (70%) patients presented in New York Heart Association class I, 4 patients presented with embolic stroke, and 4 patients presented with atrial arrhythmias. All patients underwent echocardiography on admission, intraoperatively, at discharge, and at follow-up evaluation. Eight patients additionally required mitral valve replacement (n = 1), tricuspid valve replacement (n = 1), mitral valve repair (n = 2), mini-maze (n = 1), and closure of patent foramen ovale (n = 3). Mean follow-up was 3.4 +/- 2.7 years.
Mean endoaortic-balloon clamp and endocardiopulmonary bypass times were 68.8 +/- 30.8 minutes and 112.2 +/- 41.5 minutes, respectively. There were no conversions to sternotomy. Tumors resected were classified as left atrial myxoma (n = 20), right atrial myxoma (n = 3), lipoma (n = 1), intravenous leiomyoma involving the inferior vena cava and the tricuspid valve (n = 1), plexiform tumor of the sinoatrial node (n = 1), and papillary fibroelastoma of aortic valve noncoronary cusp (n = 1). There were no hospital deaths. Mean intensive care unit and hospital stays were 1.4 +/- 1.1 days and 7.3 +/- 3.4 days, respectively. Postoperative complications were evolving stroke (n = 1), re-exploration for bleeding (n = 1), and myocardial ischemia requiring stenting (n = 1). Follow-up failed to demonstrate residual or recurrent tumor. One patient had a small residual atrial septal defect. Ninety-two percent of patients appreciated the cosmetic result and fast recovery.
Endoscopic cardiac tumor resection is feasible and a valid oncologic approach with an attractive cosmetic advantage over median sternotomy.
本研究的目的是报告我们使用端口入路法进行内镜下心脏肿瘤切除术的9年经验。
1997年3月至2005年12月,27例患者(平均年龄56.2±16.9岁;70%为女性)采用体外循环和主动脉内球囊阻断技术进行内镜下心脏肿瘤切除术。19例(70%)患者纽约心脏协会心功能分级为I级,4例患者发生栓塞性卒中,4例患者出现房性心律失常。所有患者在入院时、术中、出院时及随访评估时均接受超声心动图检查。8例患者还需要进行二尖瓣置换(n = 1)、三尖瓣置换(n = 1)、二尖瓣修复(n = 2)、迷你迷宫手术(n = 1)以及卵圆孔未闭封堵术(n = 3)。平均随访时间为3.4±2.7年。
主动脉内球囊阻断和体外循环的平均时间分别为68.8±30.8分钟和112.2±41.5分钟。无一例转为胸骨正中切开术。切除的肿瘤分类为左房黏液瘤(n = 20)、右房黏液瘤(n = 3)、脂肪瘤(n = 1)、累及下腔静脉和三尖瓣的静脉内平滑肌瘤(n = 1)、窦房结丛状肿瘤(n = 1)以及主动脉瓣无冠瓣乳头纤维弹性瘤(n = 1)。无医院死亡病例。重症监护病房和住院时间的平均值分别为1.4±1.1天和7.3±3.4天。术后并发症包括进展性卒中(n = 1)、因出血再次手术(n = 1)以及需要支架置入的心肌缺血(n = 1)。随访未发现残留或复发性肿瘤。1例患者有小的残留房间隔缺损。92%的患者对美容效果和快速康复表示满意。
内镜下心脏肿瘤切除术可行,是一种有效的肿瘤治疗方法,与胸骨正中切开术相比具有吸引人的美容优势。