Fischer P, Berner P
Neurological Institute, University of Vienna, Austria.
J Neural Transm Suppl. 1991;33:39-48. doi: 10.1007/978-3-7091-9135-4_7.
Dementia of the Alzheimer's type (DAT) is the most significant disease of the aging brain. Descriptive epidemiology of DAT found a constant doubling of prevalence rates every 5 years. Analytic epidemiology so far failed to reliably detect risk factors for DAT other than age. This might depend on the difficulties encountered in the clinical diagnosis and differential diagnosis of dementia in the elderly, which are discussed with special reference to 1) the definition of dementia, to 2) the grading of severity of dementia, to 3) the differentiation between dementia and depression, and to 4) the differentiation between multi-infarct dementia and DAT.
阿尔茨海默型痴呆（DAT）是衰老大脑最主要的疾病。DAT的描述性流行病学研究发现患病率每5年持续翻倍。到目前为止，分析性流行病学未能可靠地检测出除年龄以外的DAT风险因素。这可能取决于老年痴呆临床诊断和鉴别诊断中遇到的困难，这将特别参照以下方面进行讨论：1）痴呆的定义；2）痴呆严重程度分级；3）痴呆与抑郁的鉴别；4）多发梗死性痴呆与DAT的鉴别。
