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Pioglitazone lowers blood pressure in hypertensive patients with type 2 diabetes mellitus : an open, multicentre, observational study.

作者信息

Konrad Thomas, Lübben Georg, Franzen Christine

机构信息

Institute for Metabolic Research, EU-RISC Study Center, Frankfurt, Germany.

出版信息

Clin Drug Investig. 2005;25(5):337-40. doi: 10.2165/00044011-200525050-00006.

DOI:10.2165/00044011-200525050-00006
PMID:17532671
Abstract
摘要

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Eur J Clin Invest. 2007 Sep;37(9):709-14. doi: 10.1111/j.1365-2362.2007.01854.x.
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Impact of regulatory spin of pioglitazone on prescription of antidiabetic drugs among physicians in India: A multicentre questionnaire-based observational study.吡格列酮的监管影响对印度医生开处抗糖尿病药物的影响：一项基于多中心问卷的观察性研究。
Indian J Med Res. 2017 Oct;146(4):468-475. doi: 10.4103/ijmr.IJMR_1416_15.
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Addition of pioglitazone to stable insulin therapy in patients with poorly controlled type 2 diabetes: results of a double-blind, multicentre, randomized study.在血糖控制不佳的2型糖尿病患者的稳定胰岛素治疗方案中加用吡格列酮：一项双盲、多中心、随机研究的结果
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Pioglitazone, a PPARgamma agonist, restores endothelial function in aorta of streptozotocin-induced diabetic rats.吡格列酮，一种过氧化物酶体增殖物激活受体γ（PPARγ）激动剂，可恢复链脲佐菌素诱导的糖尿病大鼠主动脉的内皮功能。
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Diabetes Care. 2016 May;39(5):717-25. doi: 10.2337/dc16-0041.
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Pioglitazone inhibits Toll-like receptor expression and activity in human monocytes and db/db mice.吡格列酮抑制人单核细胞和db/db小鼠中Toll样受体的表达及活性。
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本文引用的文献

1
Improved glycemic control and lipid profile in a randomized study of pioglitazone compared with acarbose in patients with type 2 diabetes mellitus.在一项2型糖尿病患者中进行的吡格列酮与阿卡波糖对比的随机研究中，血糖控制和血脂状况得到改善。
Treat Endocrinol. 2002;1(5):329-36. doi: 10.2165/00024677-200201050-00005.
2
Rosiglitazone improves insulin sensitivity, glucose tolerance and ambulatory blood pressure in subjects with impaired glucose tolerance.罗格列酮可改善糖耐量受损患者的胰岛素敏感性、葡萄糖耐量及动态血压。
Diabet Med. 2004 May;21(5):415-22. doi: 10.1111/j.1464-5491.2004.01155.x.
3
Effects of the thiazolidinediones on cardiovascular risk factors.
噻唑烷二酮类药物对心血管危险因素的影响。
Am J Cardiovasc Drugs. 2002;2(3):149-56. doi: 10.2165/00129784-200202030-00002.
4
Effects of pioglitazone on metabolic control and blood pressure: a randomised study in patients with type 2 diabetes mellitus.
Curr Med Res Opin. 2003;19(6):532-9. doi: 10.1185/030079903125002180.
5
Type 2 diabetes, cardiovascular risk, and the link to insulin resistance.2型糖尿病、心血管风险以及与胰岛素抵抗的关联。
Clin Ther. 2003;25 Suppl B:B4-31. doi: 10.1016/s0149-2918(03)80240-0.
6
Thiazolidinediones in type 2 diabetes mellitus: current clinical evidence.噻唑烷二酮类药物在2型糖尿病中的应用：当前临床证据
Drugs. 2003;63(13):1373-405. doi: 10.2165/00003495-200363130-00004.
7
Effects of pioglitazone in nondiabetic patients with arterial hypertension: a double-blind, placebo-controlled study.吡格列酮对非糖尿病高血压患者的影响：一项双盲、安慰剂对照研究。
J Clin Endocrinol Metab. 2002 Dec;87(12):5503-6. doi: 10.1210/jc.2002-020963.
8
A comparison of the effects of rosiglitazone and glyburide on cardiovascular function and glycemic control in patients with type 2 diabetes.罗格列酮与格列本脲对2型糖尿病患者心血管功能和血糖控制影响的比较。
Diabetes Care. 2002 Nov;25(11):2058-64. doi: 10.2337/diacare.25.11.2058.
9
Metabolic and additional vascular effects of thiazolidinediones.噻唑烷二酮类药物的代谢及其他血管效应。
Drugs. 2002;62(10):1463-80. doi: 10.2165/00003495-200262100-00004.
10
Insulin-resistant prediabetic subjects have more atherogenic risk factors than insulin-sensitive prediabetic subjects: implications for preventing coronary heart disease during the prediabetic state.胰岛素抵抗的糖尿病前期受试者比胰岛素敏感的糖尿病前期受试者具有更多的动脉粥样硬化危险因素：对在糖尿病前期状态下预防冠心病的启示。
Circulation. 2000 Mar 7;101(9):975-80. doi: 10.1161/01.cir.101.9.975.