McGrath Kevin M, Krasinskas Alyssa M, Federle Michael P
Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, M2, C-Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
Gastroenterol Clin North Am. 2007 Jun;36(2):377-90, ix-x. doi: 10.1016/j.gtc.2007.03.016.
Intraductal papillary mucinous neoplasia is a neoplastic disorder of varying degree and extent that affects the pancreatic ductal epithelium. Clinical presentations may vary from an asymptomatic incidental finding to obstructive jaundice. Harbingers of malignancy include symptoms of jaundice, weight loss, or new-onset diabetes. In the absence of findings that correlate with malignancy, natural history is unknown. Management of these patients is controversial, and should be individualized based on surgical risk.
导管内乳头状黏液性肿瘤是一种程度和范围各异的肿瘤性疾病，累及胰腺导管上皮。临床表现可能从无症状的偶然发现到梗阻性黄疸不等。恶性肿瘤的先兆包括黄疸、体重减轻或新发糖尿病等症状。在没有与恶性肿瘤相关的发现时，其自然病程尚不清楚。这些患者的治疗存在争议，应根据手术风险进行个体化处理。
