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SWIMRT:一种使用滑动窗口算法构建注量图机器文件的图形用户界面。

SWIMRT: a graphical user interface using sliding window algorithm to construct a fluence map machine file.

作者信息

Chow James C L, Grigorov Grigor N, Yazdani Nuri

机构信息

Radiation Medicine Program and Department of Radiation Oncology, Princess Margaret Hospital, University Health Network, University of Toronto, 610 University Avenue, Toronto, ON, Canada.

出版信息

J Appl Clin Med Phys. 2006 May 25;7(2):69-85. doi: 10.1120/jacmp.v7i2.2231.

Abstract

A custom-made computer program, SWIMRT, to construct "multileaf collimator (MLC) machine" file for intensity-modulated radiotherapy (IMRT) fluence maps was developed using MATLAB and the sliding window algorithm. The user can either import a fluence map with a graphical file format created by an external treatment-planning system such as Pinnacle3 or create his or her own fluence map using the matrix editor in the program. Through comprehensive calibrations of the dose and the dimension of the imported fluence field, the user can use associated image-processing tools such as field resizing and edge trimming to modify the imported map. When the processed fluence map is suitable, a "MLC machine" file is generated for our Varian 21 EX linear accelerator with a 120-leaf Millennium MLC. This machine file is transferred to the MLC console of the LINAC to control the continuous motions of the leaves during beam irradiation. An IMRT field is then irradiated with the 2D intensity profiles, and the irradiated profiles are compared to the imported or modified fluence map. This program was verified and tested using film dosimetry to address the following uncertainties: (1) the mechanical limitation due to the leaf width and maximum traveling speed, and (2) the dosimetric limitation due to the leaf leakage/transmission and penumbra effect. Because the fluence map can be edited, resized, and processed according to the requirement of a study, SWIMRT is essential in studying and investigating the IMRT technique using the sliding window algorithm. Using this program, future work on the algorithm may include redistributing the time space between segmental fields to enhance the fluence resolution, and readjusting the timing of each leaf during delivery to avoid small fields. Possible clinical utilities and examples for SWIMRT are given in this paper.

摘要

利用MATLAB和滑动窗口算法,开发了一个定制的计算机程序SWIMRT,用于构建适形调强放疗(IMRT)注量图的“多叶准直器(MLC)机器”文件。用户既可以导入由外部治疗计划系统(如Pinnacle3)创建的图形文件格式的注量图,也可以使用程序中的矩阵编辑器创建自己的注量图。通过对导入的注量场的剂量和尺寸进行全面校准,用户可以使用诸如场大小调整和边缘裁剪等相关图像处理工具来修改导入的图。当处理后的注量图合适时,会为我们配备120叶Millennium MLC的Varian 21 EX直线加速器生成一个“MLC机器”文件。该机器文件被传输到直线加速器的MLC控制台,以控制束流照射期间叶片的连续运动。然后用二维强度分布照射IMRT野,并将照射后的分布与导入或修改后的注量图进行比较。使用胶片剂量测定法对该程序进行了验证和测试,以解决以下不确定性问题:(1)由于叶片宽度和最大行进速度导致的机械限制,以及(2)由于叶片泄漏/透射和半影效应导致的剂量测定限制。由于注量图可以根据研究要求进行编辑、调整大小和处理,SWIMRT对于使用滑动窗口算法研究和调查IMRT技术至关重要。使用该程序,该算法未来的工作可能包括重新分配分段野之间的时间空间以提高注量分辨率,以及在照射期间重新调整每个叶片的定时以避免小射野。本文给出了SWIMRT可能的临床应用和示例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a95/5722447/3784572b2933/ACM2-7-069-g001.jpg

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