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将安装在直线加速器头部作为三级准直器的80叶多叶准直器的辐射野中叶片位置的剂量学效应评估。

Evaluation of dosimetric effect of leaf position in a radiation field of an 80 leaf multileaf collimator fitted to the LINAC head as tertiary collimator.

作者信息

Kehwar Than S, Bhardwaj Anup K, Chakarvarti Shiv K

机构信息

Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA.

出版信息

J Appl Clin Med Phys. 2006 Aug 24;7(3):43-54. doi: 10.1120/jacmp.v7i3.2310.

Abstract

This study evaluates changes in the dosimetric characteristics of a Varian Millennium 80-leaf multileaf collimator (MLC) in a radiation field. In this study, dose rate, scatter factor, percentage depth dose, surface dose and dose in the buildup region, beam profile, flatness and symmetry, and penumbra width measurements were made for 6-MV and 15-MV photon beams. Analysis of widths between 50% dose levels of the beam profiles to reflect the field size at the level of profile measurement shows a significant difference between the fields defined by MLC and/or jaws and MLC (zero gap) and the fields defined by jaws only. The position of the MLC leaves in the radiation field also significantly affects scatter factors. A new relationship has, therefore, been established between the scatter factors and the position of the MLC, which will indeed be useful in the dose calculation for irregular fields. Penumbra widths increase with field size and were higher for fields defined by jaws and/or MLC than jaws and MLC (zero gap) by 1.5 mm to 4.2 mm and 3.8 mm to 5.0 mm, for 6-MV, and 1.5 mm to 2.4 mm and 3.0 mm to 5.6 mm, for 15-MV, at 20% to 80% and 10% to 90% levels, respectively. The surface dose and the dose in the buildup region were smaller for fields defined by jaws and MLC (zero gap) than the fields defined by jaws and/or MLC for both photon energies. No significant differences were found in percentage depth dose beyond dmax, beam profiles above 80% dose level, and flatness and symmetry for both energies. The results of this study suggest that while one collects linear accelerator beam data with a MLC, the effects of the positions of the MLC leaves play an important role in dosimetric characteristics of 3D conformal radiation therapy as well as intensity-modulated radiotherapy.

摘要

本研究评估了瓦里安 Millennium 80 叶多叶准直器(MLC)在辐射野中的剂量学特征变化。在本研究中,对 6MV 和 15MV 光子束进行了剂量率、散射因子、百分深度剂量、表面剂量和建成区剂量、射野轮廓、平坦度和对称性以及半值层宽度测量。分析射野轮廓 50%剂量水平之间的宽度以反映轮廓测量水平处的射野大小,结果显示由 MLC 和/或铅门以及 MLC(零间隙)定义的射野与仅由铅门定义的射野之间存在显著差异。MLC 叶片在辐射野中的位置也会显著影响散射因子。因此,已在散射因子与 MLC 的位置之间建立了一种新的关系,这对于不规则射野的剂量计算确实很有用。半值层宽度随射野大小增加,对于 6MV,由铅门和/或 MLC 定义的射野比铅门和 MLC(零间隙)定义的射野分别在 20%至 80%和 10%至 90%水平时高 1.5 毫米至 4.2 毫米和 3.8 毫米至 5.0 毫米;对于 15MV,分别高 1.5 毫米至 2.4 毫米和 3.0 毫米至 5.6 毫米。对于两种光子能量,由铅门和 MLC(零间隙)定义的射野的表面剂量和建成区剂量均小于由铅门和/或 MLC 定义的射野。在两种能量下,超过 dmax 的百分深度剂量、高于 80%剂量水平的射野轮廓以及平坦度和对称性方面均未发现显著差异。本研究结果表明,当使用 MLC 收集直线加速器束数据时,MLC 叶片位置的影响在三维适形放射治疗以及调强放射治疗的剂量学特征中起着重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5269/5722428/15be3f7c2e71/ACM2-7-43-g001.jpg

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