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螺旋断层放射治疗系统的射野外剂量测定

Out-of-field dosimetry measurements for a helical tomotherapy system.

作者信息

Ramsey Chester, Seibert Rebecca, Mahan Stephen L, Desai Dharmin, Chase Daniel

机构信息

Thompson Cancer Survival Center, Department of Radiation Oncology, Knoxville, Tennessee 37916, USA.

出版信息

J Appl Clin Med Phys. 2006 Aug 24;7(3):1-11. doi: 10.1120/jacmp.v7i3.2212.

Abstract

Helical tomotherapy is a rotational delivery technique that uses intensity-modulated fan beams to deliver highly conformal intensity-modulated radiation therapy (IMRT). The beam-on time needed to deliver a given prescribed dose can be up to 15 times longer than that needed using conventional treatment delivery. As such, there is concern that this delivery technique has the potential to increase the whole body dose due to increased leakage. The purpose of this work is to directly measure out-of-field doses for a clinical tomotherapy system. Peripheral doses were measured in-phantom using static fields and rotational intensity-modulated delivery. In-air scatter and leakage doses were also measured at multiple locations around the treatment room. At 20 cm, the tomotherapy peripheral dose dropped to 0.4% of the prescribed dose. Leakage accounted for 94% of the in-air dose at distances greater than 60 cm from the machine's isocenter. The largest measured dose equivalent rate was 1 x 10(-4) Sv/s in the plane of gantry rotation due to head leakage and primary beam transmission through the system's beam stopper. The dose equivalent rate dropped to 1 x 10(-6) Sv/s at the end of the treatment couch. Even though helical tomotherapy treatment delivery requires beam-on times that are 5 to 15 times longer than those used by conventional accelerators, the delivery system was designed to maximize shielding for radiation leakage. As such, the peripheral doses are equal to or less than the published peripheral doses for IMRT delivery on other linear accelerators. In addition, the shielding requirements are also similar to conventional linear accelerators.

摘要

螺旋断层放射治疗是一种旋转照射技术,它使用强度调制扇形束来实施高度适形的调强放射治疗(IMRT)。给予规定剂量所需的束流开启时间可能比使用传统治疗照射方式所需的时间长15倍。因此,人们担心这种照射技术可能因泄漏增加而导致全身剂量增加。这项工作的目的是直接测量临床断层放射治疗系统的野外剂量。使用静态野和旋转调强照射在模体中测量周边剂量。还在治疗室周围的多个位置测量了空气中的散射剂量和泄漏剂量。在20厘米处,断层放射治疗的周边剂量降至规定剂量的0.4%。在距离机器等中心大于60厘米的距离处,泄漏占空气中剂量的94%。由于机头泄漏和原射线束透过系统的束流阻挡器,在机架旋转平面内测得的最大剂量当量率为1×10⁻⁴Sv/s。在治疗床末端,剂量当量率降至1×10⁻⁶Sv/s。尽管螺旋断层放射治疗所需的束流开启时间比传统加速器长5至15倍,但该照射系统的设计旨在最大程度地屏蔽辐射泄漏。因此,周边剂量等于或低于其他直线加速器上IMRT照射所公布的周边剂量。此外,屏蔽要求也与传统直线加速器类似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb9/5722430/b412c37fdf8a/ACM2-7-01b-g001.jpg

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