印度芒格洛尔铅作业工人的临床表现。

Clinical manifestations of lead workers of Mangalore, India.

作者信息

Kuruvilla Ajee, Pillay V V, Adhikari Prabha, Venkatesh T, Chakrapani M, Rao H T Jayaprakash, Bastia Binaya K, Rajeev A, Saralaya K M, Rai Maneesh

机构信息

Department of Forensic Medicine, Kasturba Medical College, Mangalore, India.

出版信息

Toxicol Ind Health. 2006 Oct;22(9):405-13. doi: 10.1177/0748233706074174.

DOI:10.1177/0748233706074174

PMID:17533812

Abstract

OBJECTIVE

To correlate blood lead levels and clinical manifestations.

PARTICIPANTS

Battery workers and painters (occupationally exposed to lead in and around Mangalore, India) and occupationally unexposed controls.

MAIN OUTCOME MEASURES

We measured the blood lead levels by anodic stripping voltammetry, and a clinical examination was carried out on all participants.

RESULTS

There was a statistically significant difference between the lead-exposed group and controls with respect to clinical manifestations. The prominent findings among the lead-exposed group were fatigue, abdominal colic, abdominal discomfort, backache, muscular exhaustability, myalgia and paresthesia, at a blood lead level ranging from 0.4 to 116.6 microg/dL.

CONCLUSIONS

Such a study on battery workers and painters has not been reported in India. Several attempts have been made over the years to relate blood lead levels to adverse health effects. It was not possible to determine a precise blood lead level below which symptoms never occur or a blood lead level at which symptoms are always reported.

摘要