Thomas Jim A
Department of Chemistry, University of Sheffield, Sheffield, UK.
Chem Soc Rev. 2007 Jun;36(6):856-68. doi: 10.1039/b415246h. Epub 2007 Feb 15.
In the last ten to fifteen years, self-assembly has been increasingly employed to construct discrete supramolecular structures. In most cases, due to the thermodynamic factors that drive the self-assembly process, the final architectures produced by this approach are not kinetically robust. Thus, when robust structures are required a "self-assembly followed by covalent modification" strategy has been commonly applied. However, over the last decade an alternative strategy has emerged. Several methods for "locking" self-assembly, and thus yielding kinetically inert products have been developed. This review outlines the main strategies that have been employed towards such aims and describes some of the properties that result from the enhanced stability of product architectures.
在过去的十到十五年间，自组装越来越多地被用于构建离散的超分子结构。在大多数情况下，由于驱动自组装过程的热力学因素，这种方法产生的最终结构在动力学上并不稳定。因此，当需要稳定结构时，通常会采用“自组装后进行共价修饰”的策略。然而，在过去十年中出现了另一种策略。已经开发出几种“锁定”自组装的方法，从而产生动力学惰性产物。本综述概述了为实现这些目标所采用的主要策略，并描述了产物结构稳定性增强所带来的一些性质。
