Rapid development of band keratopathy of corneal graft associated with treatment with intracameral recombinant tissue plasminogen activator for postoperative fibrin reaction.
作者信息
Spitzer M S, Szurman P, Aisenbrey S, Rohrbach J M
机构信息
Department of Ophthalmology I, University of Tübingen, Tubingen, Germany.
出版信息
Eur J Ophthalmol. 2007 May-Jun;17(3):433-6. doi: 10.1177/112067210701700328.
PURPOSE
To report a corneal transplant complication associated with intracameral recombinant tissue plasminogen activator (rTPA) treatment of postoperative fibrin reaction.
METHODS
In a 71-year-old patient, a triple procedure was performed for perforated rheumatic ulcer and secondary cataract.
RESULTS
A dense band keratopathy developed rapidly within 36 hours after the use of intracameral injection of rTPA for the treatment of a dense fibrin clot.
CONCLUSIONS
This is the first report of rapid development of massive band keratopathy in a corneal graft after triple procedure and treatment with intracameral rTPA. Intracameral rTPA should be used with caution in patients with attenuated endothelium.
Zotero 插件