Short data-acquisition times improve projection images of lung tissue.

MR images of laboratory rat lungs that resolve the thin membranes that separate lung lobes are presented. It appears that the capabilities of in vivo small-animal pulmonary MRI may rival those of in vivo small-animal X-ray CT. Free induction decay (FID)-projection imaging was employed with particular attention to the choice of acquisition time. For a given nominal resolution, one obtains optimal point discrimination when the acquisition time T(acq) normalized by the signal decay time constant T(2)(*) is approximately 0.8-0.9, although a better signal-to-noise ratio (SNR) is obtained when this quotient is 1.6. Currently available equipment should be able to even exceed the results presented herein.