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犬小孢子菌:一所小学疫情报告

Microsporum canis: report of a primary school outbreak.

作者信息

Grills Claire E, Bryan Paul L, O'Moore Eammon, Venning Vanessa A

机构信息

Department of Dermatology, Churchill Hospital, Oxford, UK.

出版信息

Australas J Dermatol. 2007 May;48(2):88-90. doi: 10.1111/j.1440-0960.2007.00342.x.

Abstract

Microsporum canis is the causative organism in less than 10% of all tinea capitis infections in the UK. Transmission is generally via contact with an infected family pet and there are only rare reports of case clustering. This article describes an outbreak of M. canis in a primary school classroom demonstrating human-to-human spread from an index case who was presumed to have acquired the infection prior to arriving in the UK. There was no suggestion of clinical improvement following 4 weeks of oral terbinafine 125 mg daily and treatment was changed to griseofulvin. The Health Protection team screened class members and confirmed cases (either clinically or mycologically) were also treated with griseofulvin 10-20 mg/kg/day for 10 weeks. Classmates and siblings of classmates were recommended to use selenium sulphide or ketoconazole-containing shampoo twice weekly.

摘要

犬小孢子菌在英国所有头癣感染病例中所占比例不到10%。传播通常是通过接触受感染的家庭宠物,仅有罕见的病例聚集报告。本文描述了一所小学教室里发生的犬小孢子菌疫情,显示出从一名在抵达英国之前推测已感染的索引病例发生了人际传播。每日口服125毫克特比萘芬4周后,未见临床改善迹象,治疗改为灰黄霉素。健康保护团队对班级成员进行了筛查,确诊病例(临床或真菌学确诊)也接受了为期10周、每日10 - 20毫克/千克的灰黄霉素治疗。建议同班同学及其兄弟姐妹每周使用两次含硫化硒或酮康唑的洗发水。

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