[一例支气管哮喘治疗后茶碱诱发横纹肌溶解症的病例]
[A case of theophylline-induced rhabdomyolysis following therapy of bronchial asthma].
作者信息
Aoshima M, Kameyama S, Murai Y, Yamazaki M, Kamiya T, Miyazaki T
机构信息
Department of Respiratory Diseases, Tokyo Metropolitan Tama Geriatric Hospital, Japan.
出版信息
Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Aug;29(8):1064-9.
A case of a 81-year-old asthmatic male with Theophylline-induced rhabdomyolysis was reported. After intravenous administration of 250 mg of Aminophylline, he developed muscle weakness in the lower extremities. Serum CPK was 31,450 IU, and other enzymes escaping from skeletal muscles were elevated. Serum and urine myoglobin were also elevated. Cessation of Theophylline administration and conservative therapy resulted in improvement of rhabdomyolysis without concomitant acute renal failure. The present case was the 11th case of Theophylline-induced rhabdomyolysis in the world and the second case Japan.
报告了一例81岁的哮喘男性因茶碱诱发横纹肌溶解症的病例。静脉注射250毫克氨茶碱后，他出现下肢肌肉无力。血清肌酸磷酸激酶（CPK）为31450国际单位，其他从骨骼肌释放的酶也升高。血清和尿液中的肌红蛋白也升高。停用茶碱并采取保守治疗后，横纹肌溶解症得到改善，未并发急性肾衰竭。该病例是世界上第11例茶碱诱发的横纹肌溶解症病例，也是日本的第二例。
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