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一名未被识别出患有恶性胰岛素瘤的患者在使用长效奥曲肽后发生严重低血糖症。

Severe hypoglycaemia after long-acting octreotide in a patient with an unrecognized malignant insulinoma.

作者信息

Healy M L, Dawson S J, Murray R M L, Zalcberg J, Jefford M

机构信息

Division of Haematology and Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

出版信息

Intern Med J. 2007 Jun;37(6):406-9. doi: 10.1111/j.1445-5994.2007.01371.x.

DOI:10.1111/j.1445-5994.2007.01371.x
PMID:17535385
Abstract

Insulinomas are the most common hormone-producing pancreatic neuroendocrine tumours (NETs), and patients usually present with symptoms secondary to hypoglycaemia. Octreotide has been widely used in the symptomatic treatment of patients with pancreatic NETs, including insulinomas. We describe a case of a patient with a metastatic NET, subsequently identified as a malignant insulinoma, who developed severe hypoglycaemia after treatment with long-acting octreotide.

摘要

胰岛素瘤是最常见的产生激素的胰腺神经内分泌肿瘤(NETs),患者通常表现出继发于低血糖的症状。奥曲肽已广泛用于胰腺NETs患者的对症治疗,包括胰岛素瘤。我们描述了一例转移性NET患者的病例,该患者随后被确诊为恶性胰岛素瘤,在接受长效奥曲肽治疗后出现了严重低血糖。

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Severe hypoglycaemia after long-acting octreotide in a patient with an unrecognized malignant insulinoma.一名未被识别出患有恶性胰岛素瘤的患者在使用长效奥曲肽后发生严重低血糖症。
Intern Med J. 2007 Jun;37(6):406-9. doi: 10.1111/j.1445-5994.2007.01371.x.
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[Insulinoma and octreotide].[胰岛素瘤与奥曲肽]
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Short- and long-term somatostatin analogue treatment in patients with hypoglycaemia related to endogenous hyperinsulinism.内源性高胰岛素血症相关低血糖患者的短期和长期生长抑素类似物治疗
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