Imafuku Shinichi, Yoshimura Daisuke, Moroi Yoichi, Urabe Kazunori, Furue Masutaka
Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka city, Japan.
J Dermatol. 2007 Jun;34(6):387-9. doi: 10.1111/j.1346-8138.2007.00294.x.
Angioimmunoblastic T-cell lymphoma (AITL) is a rare subtype of peripheral T-cell lymphoma that causes immunological disorders such as immunosuppression, autoimmune disease-like symptoms and allergy. We report a case of a 67-year-old man with AITL who had a serious varicella zoster virus (VZV) reinfection that appeared clinically to be varicella. Forty percent of cases of AITL are associated with skin rash. A variety of cutaneous manifestations have been reported; however, the majority are macropapular eruptions that are often diagnosed as drug associated. Our study emphasizes the need to correctly diagnose opportunistic infections, such as the varicella that is documented in our patient, at early stages in AITL.
血管免疫母细胞性T细胞淋巴瘤（AITL）是外周T细胞淋巴瘤的一种罕见亚型，可引发免疫紊乱，如免疫抑制、自身免疫病样症状和过敏反应。我们报告一例67岁患AITL的男性病例，该患者发生严重的水痘带状疱疹病毒（VZV）再次感染，临床症状表现为水痘。40%的AITL病例与皮疹有关。已有多种皮肤表现的报道；然而，大多数是斑丘疹，常被诊断为药物相关性皮疹。我们的研究强调，在AITL早期需要正确诊断机会性感染，如我们患者所记录的水痘。
