A simplified recipe for prions.
作者信息
Lee Kil Sun, Caughey Byron
机构信息
Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA.
出版信息
Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9551-2. doi: 10.1073/pnas.0703910104. Epub 2007 May 29.
Abstract
摘要
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本文引用的文献
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Formation of native prions from minimal components in vitro.在体外由最小成分形成天然朊病毒。
Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9741-6. doi: 10.1073/pnas.0702662104. Epub 2007 May 29.
2
Stress and prions: lessons from the yeast model.应激与朊病毒：来自酵母模型的启示。
FEBS Lett. 2007 Jul 31;581(19):3695-701. doi: 10.1016/j.febslet.2007.04.075. Epub 2007 May 8.
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Prions and their partners in crime.朊病毒及其帮凶。
Nature. 2006 Oct 19;443(7113):803-10. doi: 10.1038/nature05294.
4
The most infectious prion protein particles.传染性最强的朊病毒蛋白颗粒。
Nature. 2005 Sep 8;437(7056):257-61. doi: 10.1038/nature03989.
5
Immunodetection of disease-associated mutant PrP, which accelerates disease in GSS transgenic mice.对与疾病相关的突变型朊蛋白进行免疫检测，该突变型朊蛋白会加速格斯特曼综合征转基因小鼠的疾病进程。
EMBO J. 2005 Jul 6;24(13):2472-80. doi: 10.1038/sj.emboj.7600717. Epub 2005 Jun 16.
6
Anchorless prion protein results in infectious amyloid disease without clinical scrapie.无锚定朊病毒蛋白导致传染性淀粉样疾病，无临床瘙痒病症状。
Science. 2005 Jun 3;308(5727):1435-9. doi: 10.1126/science.1110837.
7
Protease-resistant prion protein amplification reconstituted with partially purified substrates and synthetic polyanions.用部分纯化的底物和合成聚阴离子重建蛋白酶抗性朊病毒蛋白扩增。
J Biol Chem. 2005 Jul 22;280(29):26873-9. doi: 10.1074/jbc.M503973200. Epub 2005 May 24.
8
In vitro generation of infectious scrapie prions.传染性瘙痒病朊病毒的体外生成
Cell. 2005 Apr 22;121(2):195-206. doi: 10.1016/j.cell.2005.02.011.
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Heparan sulfate is a cellular receptor for purified infectious prions.硫酸乙酰肝素是纯化感染性朊病毒的细胞受体。
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PrPSc incorporation to cells requires endogenous glycosaminoglycan expression.朊病毒蛋白（PrPSc）进入细胞需要内源性糖胺聚糖的表达。
J Biol Chem. 2005 Apr 29;280(17):17057-61. doi: 10.1074/jbc.M411314200. Epub 2005 Jan 24.
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