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[分子量为67kD的抗原循环抗体检测与感染性-过敏性心肌炎临床表现严重程度之间的关系]

[Relationship between the detection of circulating antibodies to antigen with a molecular weight of 67 kD and the severity of clinical manifestations of infectious-allergic myocarditis].

作者信息

Tereshchenko S E, Riazanov S L, Kotelevtsev Iu V, Zimin Iu I, Beliaeva S A, Sidorenko B A

出版信息

Kardiologiia. 1991 Sep;31(9):19-21.

PMID:1753606
Abstract

Infectious allergic myocarditis (IAM) is frequently complicated by signs of congestive heart failure (CHF). IAM patients generally suffer from rhythm and conduction disturbances which can be the leading symptom of the disease in some patients. Slowly progressive immune inflammation in the myocardium makes the differential diagnosis difficult in IAM and dilated cardiomyopathy in which endomyocardial biopsy and cardiospecific immunological examinations of the patient are of great significance. Identification of the autoimmune process in the myocardium and early immunodepressive therapy may arrest the progression of myocardial damage. The purpose of the present study was to examine the relationship between antigen antibodies and clinical manifestations of myocardial damage in IAM.

摘要

感染性过敏性心肌炎(IAM)常并发充血性心力衰竭(CHF)体征。IAM患者通常会出现节律和传导紊乱,在某些患者中这可能是该疾病的主要症状。心肌中缓慢进展的免疫炎症使得IAM与扩张型心肌病的鉴别诊断困难,而患者的心内膜心肌活检和心肌特异性免疫学检查具有重要意义。识别心肌中的自身免疫过程并进行早期免疫抑制治疗可能会阻止心肌损伤的进展。本研究的目的是探讨IAM中抗原抗体与心肌损伤临床表现之间的关系。

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