Hsu Peng-Wei, Chang Cheng-Nen, Tseng Chen-Kan, Wei Kuo-Cheng, Wang Chun-Chieh, Chuang Chi-Cheng, Huang Yin-Cheng
Brain Division of Neurosurgery, Department of Surgery, Chang Gung Memorial Hospital, Tao Yuan, Taiwan, ROC.
Cerebrovasc Dis. 2007;24(1):116-20; discussion 121. doi: 10.1159/000103126. Epub 2007 May 23.
Epilepsy is the most common symptom of cavernoma. Although microsurgery is the mainstay treatment for epileptogenic cavernoma, this procedure may cause severe complications for some lesions. This report aimed to study if linear accelerator (LINAC) radiosurgery was an alternative treatment modality for epileptogenic cavernoma.
In this retrospective study, 29 patients were diagnosed with epileptogenic cavernomas from September 1995 to March 2005. Fifteen patients were treated with surgical excision and 14 with LINAC radiosurgery. The evaluation of epilepsy control was according to Engel's classification.
In the surgical group, 13 (86.7%) of 15 patients had a class I seizure-free outcome. In the radiosurgery group, class I control was achieved in 9 (64.3%) of 14 patients. However, there was no significant difference in the results of treatment between the two groups.
LINAC radiosurgery is an alternative treatment for epileptogenic cavernomas, especially when the lesions are located in the central regions or eloquent areas of the brain.
癫痫是海绵状血管瘤最常见的症状。尽管显微手术是致痫性海绵状血管瘤的主要治疗方法，但该手术对某些病变可能会导致严重并发症。本报告旨在研究直线加速器（LINAC）放射外科是否是致痫性海绵状血管瘤的一种替代治疗方式。
在这项回顾性研究中，1995年9月至2005年3月期间，29例患者被诊断为致痫性海绵状血管瘤。15例患者接受了手术切除治疗，14例接受了LINAC放射外科治疗。癫痫控制情况根据恩格尔分类法进行评估。
手术组中，15例患者中有13例（86.7%）达到I级无癫痫发作结果。在放射外科组中，14例患者中有9例（64.3%）达到I级控制。然而，两组治疗结果无显著差异。
LINAC放射外科是致痫性海绵状血管瘤的一种替代治疗方法，尤其是当病变位于脑中央区域或功能区时。
