Fulciniti Franco, Botti Gerardo, De Chiara Annarosaria, Parlato Vincenzo, Russo Serena, Vosa Laura, Nappi M Michela
Department of Pathology, National Cancer Institute of Naples G. Pascale Foundation, Naples, Italy.
Acta Cytol. 2007 May-Jun;51(3):385-9. doi: 10.1159/000325752.
To describe the cytopathologic findings in a case of alveolar rhabdomyosarcoma (ARMS) of the perineum in a 13-year-old girl and to compare the cytopathologic findings with the histopathologic and immunohistochemical features observed on the corresponding fragments obtained from core biopsy of the mass.
The cytopathologic findings observed in fine needle aspiration biopsy of a vulvar mass were analyzed with reference to their predictive diagnostic value in pathologic evaluation of the lesion.
Following a prospective cytopathologic diagnosis of ARMS, a cutting needle core biopsy was performed. Histopathologic and immunohistochemical study of the tissue fragments confirmed the cytopathologic diagnosis.
Careful cytopathologic evaluation of optimal cell samples from ARMS may elicit a correct diagnosis provided that immunocytochemical staining for markers of myogenic differentiation is performed in a pretherapeutic phase.
描述一名13岁女孩会阴部肺泡横纹肌肉瘤（ARMS）病例的细胞病理学发现，并将细胞病理学发现与从肿块芯针活检获得的相应组织切片上观察到的组织病理学和免疫组织化学特征进行比较。
分析在外阴肿块细针穿刺活检中观察到的细胞病理学发现，参考其在病变病理评估中的预测诊断价值。
在对ARMS进行前瞻性细胞病理学诊断后，进行了切割针芯针活检。组织切片的组织病理学和免疫组织化学研究证实了细胞病理学诊断。
只要在治疗前阶段对肌源性分化标志物进行免疫细胞化学染色，对ARMS的最佳细胞样本进行仔细的细胞病理学评估可能会得出正确的诊断。
