Taylor Anna K, Cousins Rachel, Butt Warwick W
Intensive Care Unit, Royal Children's Hospital, Melbourne, VIC, Australia.
Crit Care Resusc. 2007 Jun;9(2):172-7.
To evaluate the long-term functional status and quality of life of infants and children who have received extracorporeal life support (ECLS), and to determine how and when death occurred.
Long-term, prospective follow-up study.
16-bed paediatric intensive care unit in a university teaching hospital.
All children who received ECLS in the period April 1988 to October 2000 in the paediatric ICU at the Royal Children's Hospital, Melbourne, VIC.
The records of all 224 children who had received ECLS were reviewed, and functional status and quality of life were assessed through interview with each child's parent or guardian for those who had survived.
Follow-up information was available for 211 children at a median of 7.2 years (range, 3.9 months to 12.6 years) after admission to the paediatric ICU. Sixty-nine children were alive at follow-up, 96% of whom were likely to lead an independent existence. Of the 142 deaths, 123 occurred in the paediatric ICU: 74 were due to elective withdrawal of therapy for poor prognosis, and eight for brain death; 30 were disease-related; seven were ECLSrelated; and four were due to sepsis.
ECLS is a complex therapy which has been used in Australian children for 18 years; a third of children survived long term, and 96% of these had a favourable outcome.
评估接受体外生命支持（ECLS）的婴幼儿及儿童的长期功能状况和生活质量，并确定死亡的方式和时间。
长期前瞻性随访研究。
一所大学教学医院的16张床位的儿科重症监护病房。
1988年4月至2000年10月期间在墨尔本皇家儿童医院儿科重症监护病房接受ECLS的所有儿童。
回顾了所有224例接受ECLS儿童的记录，并通过与存活儿童的父母或监护人面谈来评估其功能状况和生活质量。
在入住儿科重症监护病房后，对211名儿童进行了随访，随访时间中位数为7.2年（范围为3.9个月至12.6年）。随访时有69名儿童存活，其中96%的儿童可能独立生活。在142例死亡病例中，123例发生在儿科重症监护病房：74例因预后不良而选择撤机，8例因脑死亡；30例与疾病相关；7例与ECLS相关；4例因败血症死亡。
ECLS是一种复杂的治疗方法，已在澳大利亚儿童中使用了18年；三分之一的儿童长期存活，其中96%预后良好。
