Mira E
Department of Otolaryngology and Head Neck Surgery, University of Pavia and IRCCS Policlinico San Matteo, Pavia, Italy.
Int J Clin Pract. 2008 Jan;62(1):109-14. doi: 10.1111/j.1742-1241.2006.01091.x. Epub 2007 May 30.
Vertigo, dizziness and imbalance are the main symptoms of vestibular disorders. They can lead to physical consequences, such as reduced postural control and falls, to psychologic/psychiatric consequences, such as anxiety-depression symptoms, panic and agoraphobia, and to cognitive defects, especially in the elderly. Consequently, the general health status and the quality of life (QoL) of vestibular patients can be significantly impaired. Several questionnaires have been developed in an attempt to quantify the degree of handicap and disability, the self-perceived health status and the quality of life in vestibular patients with dizziness and imbalance. Additionally, the main goal of the treatments of vestibular disorders should be to control symptoms, reduce functional disability and to improve patients' QoL. This article reviews the physical and psychological consequences of the vestibular disorders, their impact on the patients' QoL, and the treatment options, including drug prescriptions and vestibular rehabilitation protocols. A profile of the compound betahistine and its efficacy on QoL indices in the treatment of Menière's disease and other forms of peripheral vertigo is also presented.
眩晕、头晕和平衡失调是前庭疾病的主要症状。它们可导致身体方面的后果,如姿势控制能力下降和跌倒,还可导致心理/精神方面的后果,如焦虑抑郁症状、惊恐和广场恐惧症,以及认知缺陷,尤其是在老年人中。因此,前庭疾病患者的总体健康状况和生活质量(QoL)可能会受到显著损害。已经开发了几种问卷,试图量化头晕和平衡失调的前庭疾病患者的残疾程度、自我感知的健康状况和生活质量。此外,前庭疾病治疗的主要目标应该是控制症状、减少功能残疾并改善患者的生活质量。本文综述了前庭疾病的身体和心理后果、它们对患者生活质量的影响以及治疗选择,包括药物处方和前庭康复方案。还介绍了复方倍他司汀的概况及其在治疗梅尼埃病和其他形式的外周性眩晕时对生活质量指标的疗效。