• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

前庭神经鞘瘤患者致残性眩晕的经迷路手术

Translabyrinthine surgery for disabling vertigo in vestibular schwannoma patients.

作者信息

Godefroy W P, Hastan D, van der Mey A G L

机构信息

Department of Otolaryngology, Leiden University Medical Centre, Leiden, The Netherlands.

出版信息

Clin Otolaryngol. 2007 Jun;32(3):167-72. doi: 10.1111/j.1365-2273.2007.01427.x.

DOI:10.1111/j.1365-2273.2007.01427.x
PMID:17550503
Abstract

OBJECTIVE

To determine the impact of translabyrinthine surgery on the quality of life in vestibular schwannoma patients with rotatory vertigo.

STUDY DESIGN

Prospective study in 18 vestibular schwannoma patients.

SETTING

The study was conducted in a multispecialty tertiary care clinic.

PARTICIPANTS

All 18 patients had a unilateral intracanalicular vestibular schwannoma, without serviceable hearing in the affected ear and severely handicapped by attacks of rotatory vertigo and constant dizziness. Despite an initial conservative treatment, extensive vestibular rehabilitation exercises, translabyrinthine surgery was performed because of the disabling character of the vertigo, which considerably continued to affect the patients' quality of life.

MAIN OUTCOME MEASURES

Preoperative and postoperative quality of life using the Short Form 36 Health Survey (Short Form-36) scores and Dizziness Handicap Inventory (DHI) scores.

RESULTS

A total of 17 patients (94%) completed the questionnaire preoperatively and 3 and 12 months postoperatively. All Short Form-36 scales of the studied patients scored significantly lower when compared with the healthy Dutch control sample (P < 0.05). There was a significant improvement of DHI total scores and Short Form-36 scales on physical and social functioning, role-physical functioning, role-emotional functioning, mental health and general health at 12 months after surgery when compared with preoperative scores (P < 0.05).

CONCLUSIONS

Vestibular schwannoma patients with disabling vertigo, experience significant reduced quality of life when compared with a healthy Dutch population. Translabyrinthine tumour removal significantly improved the patients' quality of life. Surgical treatment should be considered in patients with small- or medium-sized tumours and persisting disabling vertigo resulting in a poor quality of life.

摘要

目的

确定经迷路手术对患有旋转性眩晕的前庭神经鞘瘤患者生活质量的影响。

研究设计

对18例前庭神经鞘瘤患者进行前瞻性研究。

研究地点

该研究在一家多专科三级护理诊所进行。

研究对象

所有18例患者均患有单侧内听道前庭神经鞘瘤,患耳无有效听力,因旋转性眩晕发作和持续性头晕而严重致残。尽管最初进行了保守治疗和广泛的前庭康复训练,但由于眩晕的致残性持续严重影响患者的生活质量,故进行了经迷路手术。

主要观察指标

使用简明健康调查问卷(Short Form-36)评分和头晕残障量表(DHI)评分评估术前和术后的生活质量。

结果

共有17例患者(94%)在术前、术后3个月和12个月完成了问卷调查。与健康的荷兰对照样本相比,所有研究患者的简明健康调查问卷各量表得分均显著较低(P<0.05)。与术前评分相比,术后12个月时,头晕残障量表总分以及简明健康调查问卷在身体和社会功能、角色-身体功能、角色-情感功能、心理健康和总体健康方面的量表得分均有显著改善(P<0.05)。

结论

与健康的荷兰人群相比,患有致残性眩晕的前庭神经鞘瘤患者生活质量显著降低。经迷路肿瘤切除术显著改善了患者的生活质量。对于患有中小型肿瘤且持续存在致残性眩晕导致生活质量较差的患者,应考虑手术治疗。

相似文献

1
Translabyrinthine surgery for disabling vertigo in vestibular schwannoma patients.前庭神经鞘瘤患者致残性眩晕的经迷路手术
Clin Otolaryngol. 2007 Jun;32(3):167-72. doi: 10.1111/j.1365-2273.2007.01427.x.
2
Postoperative quality of life in vestibular schwannoma patients measured by the SF36 Health Questionnaire.通过SF36健康调查问卷评估前庭神经鞘瘤患者术后的生活质量。
Laryngoscope. 2000 Jan;110(1):151-5. doi: 10.1097/00005537-200001000-00027.
3
Less than 1% cerebrospinal fluid leakage in 1,803 translabyrinthine vestibular schwannoma surgery cases.1803 例经迷路前庭神经鞘瘤手术中,脑脊液漏发生率不足 1%。
Otol Neurotol. 2010 Feb;31(2):276-83. doi: 10.1097/MAO.0b013e3181cc06ad.
4
Quality of life in postoperative vestibular schwannoma patients.前庭神经鞘瘤术后患者的生活质量
Laryngoscope. 2009 Nov;119(11):2252-7. doi: 10.1002/lary.20217.
5
Efficacy of microsurgical tumor removal for treatment of patients with intracanalicular vestibular schwannoma presenting with disabling vestibular symptoms.显微手术切除肿瘤治疗伴有失能性前庭症状的管内前庭神经鞘瘤患者的疗效。
J Neurosurg. 2017 May;126(5):1514-1519. doi: 10.3171/2016.4.JNS153020. Epub 2016 Jun 17.
6
Untreated vestibular schwannomas: vertigo is a powerful predictor for health-related quality of life.未经治疗的前庭神经鞘瘤:眩晕是健康相关生活质量的有力预测指标。
Neurosurgery. 2006 Jul;59(1):67-76; discussion 67-76. doi: 10.1227/01.NEU.0000219838.80931.6B.
7
Conservative treatment of vestibular schwannoma: a follow-up study on clinical and quality-of-life outcome.前庭神经鞘瘤的保守治疗:临床和生活质量结果的随访研究。
Otol Neurotol. 2009 Oct;30(7):968-74. doi: 10.1097/MAO.0b013e3181b4e3c9.
8
Patient outcomes after vestibular schwannoma management: a prospective comparison of microsurgical resection and stereotactic radiosurgery.前庭神经鞘瘤治疗后的患者预后:显微手术切除与立体定向放射外科的前瞻性比较。
Neurosurgery. 2006 Jul;59(1):77-85; discussion 77-85. doi: 10.1227/01.NEU.0000219217.14930.14.
9
Vestibular schwannoma surgery outcomes: our multidisciplinary experience in 400 cases over 17 years.前庭神经鞘瘤手术结果:我们17年间400例病例的多学科经验。
Laryngoscope. 2004 Apr;114(4):681-8. doi: 10.1097/00005537-200404000-00016.
10
Hearing preservation after classical translabyrinthine removal of a vestibular schwannoma: case report and literature review.经迷路入路经典手术切除前庭神经鞘瘤后听力保留:病例报告及文献综述
J Laryngol Otol. 2007 Jan;121(1):76-9. doi: 10.1017/S0022215106003598. Epub 2006 Oct 19.

引用本文的文献

1
Labyrinthectomy Improves Dizziness in Patients with Vestibular Schwannoma.迷路切除术可改善前庭神经鞘瘤患者的头晕症状。
J Neurol Surg B Skull Base. 2024 Jul 24;86(4):395-402. doi: 10.1055/a-2360-9474. eCollection 2025 Aug.
2
A Scoping Review on Vestibulopathy After Microsurgical Resection of Vestibular Schwannoma-The Forgotten Symptom.前庭神经鞘瘤显微手术后前庭病变的范围综述——被遗忘的症状
Neurosurg Pract. 2024 Aug 28;5(4):e00107. doi: 10.1227/neuprac.0000000000000107. eCollection 2024 Dec.
3
Functional Outcome and Balance Compensation in Patients with Unilateral Vestibular Schwannoma After Surgical Treatment-Short- and Medium-Term Observation.
单侧听神经瘤患者手术治疗后功能结局与平衡代偿——短期和中期观察
J Clin Med. 2025 Jan 17;14(2):585. doi: 10.3390/jcm14020585.
4
A first exploration of the economic consequences of an autonomous surgical robot for lateral skull base surgery: an early health technology assessment.自主手术机器人对侧颅底手术的经济后果初探:一项早期卫生技术评估。
Int J Technol Assess Health Care. 2023 Jul 31;39(1):e46. doi: 10.1017/S0266462323000430.
5
Vestibular Impairment in Patients with Vestibular Schwannoma: A Journey through the Pitfalls of Current Literature.前庭神经鞘瘤患者的前庭功能损害:探寻当前文献中的陷阱之旅
Audiol Res. 2023 Apr 13;13(2):285-303. doi: 10.3390/audiolres13020025.
6
Quality of life reporting in the management of posterior fossa tumours: A systematic review.后颅窝肿瘤治疗中的生活质量报告:一项系统综述。
Front Surg. 2022 Sep 29;9:970889. doi: 10.3389/fsurg.2022.970889. eCollection 2022.
7
Factors Influencing Personalized Management of Vestibular Schwannoma: A Systematic Review.影响前庭神经鞘瘤个体化管理的因素:一项系统评价
J Pers Med. 2022 Sep 30;12(10):1616. doi: 10.3390/jpm12101616.
8
Quality of Life After Vestibular Schwannoma Surgery: A Question of Perspective.前庭神经鞘瘤手术后的生活质量:视角问题
Front Oncol. 2022 Feb 11;11:770789. doi: 10.3389/fonc.2021.770789. eCollection 2021.
9
Auditory brainstem response prior to MRI compared to standalone MRI in the detection of vestibular schwannoma: A modelling study.听觉脑干反应在前磁共振成像与单独磁共振成像在听神经鞘瘤检测中的比较:一项建模研究。
Clin Otolaryngol. 2022 Mar;47(2):295-303. doi: 10.1111/coa.13894. Epub 2021 Nov 24.
10
Patient quality of life after vestibular schwannoma removal: possibilities and limits to measuring different domains of patients' wellbeing.前庭神经鞘瘤切除术后患者的生活质量:衡量患者不同福祉领域的可能性和局限性。
Eur Arch Otorhinolaryngol. 2019 Sep;276(9):2441-2447. doi: 10.1007/s00405-019-05499-1. Epub 2019 Jun 8.