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识别有自杀意念者自杀未遂的相关因素:一项基于人群的研究。

Identifying correlates of suicide attempts in suicidal ideators: a population-based study.

作者信息

Brezo Jelena, Paris Joel, Tremblay Richard, Vitaro Frank, Hébert Martine, Turecki Gustavo

机构信息

McGill Group for Suicide Studies, Douglas Hospital Research Center, Montreal, Canada.

出版信息

Psychol Med. 2007 Nov;37(11):1551-62. doi: 10.1017/S0033291707000803. Epub 2007 May 31.

Abstract

BACKGROUND

Identification of factors that distinguish between ideators who act on their suicidal thoughts from those who do not is an important clinical and research objective.

METHOD

We examined correlates of suicide attempts in suicidal ideators, members of a French-Canadian, school-based cohort. Suicidal thoughts were evaluated in adolescence and early adulthood in the total sample of suicidal ideators, who were then stratified into subgroups consisting of persistent ideators, male ideators and female ideators.

RESULTS

In addition to persistent suicidal ideas [odds ratios (ORs) 2.1-2.8], Axis I psychopathology, female gender and childhood sexual abuse (CSA) were the most consistent correlates of suicide attempts. Externalizing disorders were significant contributors in persistent ideators [drug misuse: OR 2.8, 95% confidence interval (CI) 1.1-6.9] and in male ideators in particular (disruptive disorders: OR 5.9, 95% CI 2.2-16.0). In women, psychiatric co-morbidity also had a significant effect (OR 1.6, 95% CI 1.1-2.1). CSA was of relevance in both women (OR 1.2, 95% CI 1.1-1.4) and persistent ideators (OR 1.3, 95% CI 1.1-1.5). Personality traits showed gender-specific contribution with affective instability (OR 1.1, 95% CI 1.01-1.1) and anxiousness (OR 1.3, 95% CI 1.1-1.7) contributing in men and disruptive aggression (OR 1.1, 95% CI 1.03-1.3) in women.

CONCLUSIONS

Correlates of suicide attempts in suicidal ideators vary as a function of the persistence of suicidal ideas and gender. This heterogeneity across subgroups of suicidal ideators may be attributed, at least in part, to differences between the sexes, early environmental adversity, maladaptive personality, and psychiatric symptoms. Further exploration and continued prospective follow-up is necessary to examine these possibilities.

摘要

背景

识别那些将自杀想法付诸行动的有自杀意念者与未付诸行动者之间的区分因素是一项重要的临床和研究目标。

方法

我们研究了一个法裔加拿大裔、以学校为基础的队列中有自杀意念者的自杀未遂相关因素。在所有有自杀意念者样本的青春期和成年早期评估自杀想法,然后将他们分层为持续有自杀意念者、男性有自杀意念者和女性有自杀意念者亚组。

结果

除了持续的自杀想法(优势比[ORs]为2.1 - 2.8)之外,轴I精神病理学、女性性别和童年期性虐待(CSA)是自杀未遂最一致的相关因素。外化性障碍在持续有自杀意念者(药物滥用:OR 2.8,95%置信区间[CI] 1.1 - 6.9)中是重要因素,在男性有自杀意念者中尤其如此(破坏性行为障碍:OR 5.9,95% CI 2.2 - 16.0)。在女性中,精神共病也有显著影响(OR 1.6,95% CI 1.1 - 2.1)。CSA在女性(OR 1.2,95% CI 1.1 - 1.4)和持续有自杀意念者(OR 1.3,95% CI 1.1 - 1.5)中都有相关性。人格特质显示出性别特异性作用,情感不稳定(OR 1.1,95% CI 1.01 - 1.1)和焦虑(OR 1.3,95% CI 1.1 - 1.7)在男性中有影响,而破坏性行为攻击(OR 1.1,95% CI 1.03 - 1.3)在女性中有影响。

结论

有自杀意念者的自杀未遂相关因素因自杀想法的持续性和性别而异。这种有自杀意念者亚组之间的异质性可能至少部分归因于性别差异、早期环境逆境、适应不良人格和精神症状。有必要进行进一步探索并持续进行前瞻性随访以研究这些可能性。

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