Gould M S, King R, Greenwald S, Fisher P, Schwab-Stone M, Kramer R, Flisher A J, Goodman S, Canino G, Shaffer D
Division of Child Psychiatry, Columbia University, New York, NY 10032, USA.
J Am Acad Child Adolesc Psychiatry. 1998 Sep;37(9):915-23. doi: 10.1097/00004583-199809000-00011.
To identify the independent and differential diagnostic and symptom correlates of suicidal ideation and suicide attempts and determine whether there are gender- and age-specific diagnostic profiles.
The relationships between suicidal ideation, suicide attempts, and psychiatric disorders were examined among 1,285 randomly selected children and adolescents, aged 9 to 17 years, of whom 42 had attempted suicide and 67 had expressed suicidal ideation only. Youths and their parents were interviewed as part of the Methods for the Epidemiology of Child and Adolescent Mental Disorders (MECA) Study, using the Diagnostic Interview Schedule for Children Version 2.3 (DISC-2.3).
Logistic regression analyses indicated that mood, anxiety, and substance abuse/dependence disorders independently increased the risk of suicide attempts, after controlling for sociodemographic characteristics. There was no significant independent contribution of disruptive disorders to suicide attempts, although its association with suicidal ideation was significant. Substance abuse/dependence independently differentiated suicide attempters from ideators. Noncriterion symptoms that remained significant predictors of suicide risk, after adjusting for psychiatric disorder, included panic attacks and aggressiveness. Perfectionism did not significantly increase suicide risk after adjusting for psychiatric disorder. The association of specific disorders and noncriterion symptoms with suicidality varied as a function of gender and age.
A monolithic diagnostic risk profile for suicidality, ignoring gender- and age-specific risks, is inadequate. The contribution of substance abuse/dependence in the escalation from suicidal thoughts to suicide attempts is underscored.
确定自杀意念和自杀未遂的独立及鉴别诊断与症状关联,并确定是否存在性别和年龄特异性的诊断特征。
在1285名随机选取的9至17岁儿童和青少年中,研究自杀意念、自杀未遂与精神障碍之间的关系,其中42人曾试图自杀,67人仅表达过自杀意念。作为儿童和青少年精神障碍流行病学方法(MECA)研究的一部分,使用儿童诊断访谈量表第2.3版(DISC - 2.3)对青少年及其父母进行访谈。
逻辑回归分析表明,在控制社会人口学特征后,情绪、焦虑和物质滥用/依赖障碍独立增加自杀未遂风险。破坏性行为障碍对自杀未遂没有显著的独立影响,尽管其与自杀意念的关联显著。物质滥用/依赖独立区分了自杀未遂者和有自杀意念者。在调整精神障碍因素后,仍为自杀风险显著预测因素的非标准症状包括惊恐发作和攻击性。调整精神障碍因素后,完美主义并未显著增加自杀风险。特定障碍和非标准症状与自杀倾向的关联因性别和年龄而异。
忽略性别和年龄特异性风险的单一自杀诊断风险特征是不充分的。强调了物质滥用/依赖在从自杀念头升级到自杀未遂过程中的作用。