Blattner Jennifer Milspaw, Gable Preston, Quigley Michael M, McHale Michael T
Department of Obstetric and Gynecology, Naval Medical Center San Diego, San Diego, CA 92134-1005, USA.
Gynecol Oncol. 2007 Aug;106(2):419-22. doi: 10.1016/j.ygyno.2007.04.008. Epub 2007 May 30.
: Primitive peripheral neuroectodermal tumors (PNETs) of the uterus are rare. Recent data have demonstrated improved response rates with adjuvant chemotherapy.
: A 26-year-old, gravida 2, para 1, Filipina female underwent an emergent cesarean section for fetal indications. Intraoperative findings were remarkable for a soft tissue mass in the lower uterine segment. Histologic features, immunohistochemical findings, and chromosomal analysis were consistent with a PNET. The patient underwent radical surgery, adjuvant chemotherapy with vincristine, doxorubicin, cyclophosphamide, ifosfamide and etoposide (VAC/IE), and whole pelvic radiation therapy.
: Only 14 case reports of primitive neuroectodermal tumors of the uterus have been published in the English literature to date. No definitive conclusions concerning the therapeutic management and prognosis have been ascertained.
子宫原发性外周神经外胚层肿瘤（PNETs）较为罕见。近期数据显示辅助化疗的缓解率有所提高。
一名26岁、孕2产1的菲律宾女性因胎儿指征行急诊剖宫产术。术中发现子宫下段有一软组织肿块。组织学特征、免疫组化结果及染色体分析均符合PNET。该患者接受了根治性手术、长春新碱、阿霉素、环磷酰胺、异环磷酰胺和依托泊苷（VAC/IE）辅助化疗以及全盆腔放疗。
迄今为止，英文文献中仅发表了14例子宫原发性神经外胚层肿瘤的病例报告。尚未确定有关治疗管理和预后的确切结论。
