Daimon Tadahisa, Johkoh Takeshi, Sumikawa Hiromitsu, Honda Osamu, Fujimoto Kiminori, Koga Takeharu, Arakawa Hiroaki, Yanagawa Masahiro, Inoue Atsuo, Mihara Naoki, Tomiyama Noriyuki, Nakamura Hironobu, Sugiyama Yukihiko
Department of Radiology, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
Eur J Radiol. 2008 Mar;65(3):462-7. doi: 10.1016/j.ejrad.2007.04.012. Epub 2007 May 29.
To determine thin-section computed tomography (CT) characteristics of acute eosinophilic pneumonia (AEP).
Thin-section CT scans of 29 patients (14 males, 15 females; mean age, 26+/-15 years; age range, 15-72 years) with AEP were included this retrospective study. The clinical diagnosis of AEP was established by Allen's criteria. Each thin-section CT was reviewed by two observers.
Bilateral areas with ground-glass attenuation were observed on thin-section CT in all patients. Areas of air-space consolidation were present in 16 (55%) of 29 patients. Poorly defined centrilobular nodules were present in 9 patients (31%). Interlobular septal thickening was present in 26 patients (90%). Thickening of bronchovascular bundles was present in 19 patients (66%). Pleural effusions were present in 23 patients (79%) (bilateral=22, right side=1, left side=0). The predominant overall anatomic distribution was central in only 2 (7%) of 29 patients, peripheral in 9 patients (31%), and random in 18 patients (62%). The overall zonal predominance was upper in 4 patients (14%), lower in 8 patients (28%), and random in 17 patients (58%).
CT findings in AEP patients consisted mainly of bilateral areas of ground-glass attenuation, interlobular septal thickening, thickening of bronchovascular bundles, and the presence of a pleural effusion without cardiomegaly. The most common overall anatomic distribution and zonal predominance of the abnormal CT findings were random.
确定急性嗜酸性粒细胞性肺炎（AEP）的薄层计算机断层扫描（CT）特征。
本回顾性研究纳入了29例AEP患者（男14例，女15例；平均年龄26±15岁；年龄范围15 - 72岁）的薄层CT扫描图像。AEP的临床诊断依据艾伦标准确立。两位观察者对每例薄层CT进行了评估。
所有患者的薄层CT均显示双侧磨玻璃样密度减低区。29例患者中有16例（55%）出现实变影。9例患者（31%）出现边界不清的小叶中心结节。26例患者（90%）出现小叶间隔增厚。19例患者（66%）出现支气管血管束增粗。23例患者（79%）出现胸腔积液（双侧22例，右侧1例，左侧0例）。29例患者中仅2例（7%）主要解剖分布为中央型，9例（31%）为周边型，18例（62%）为随机型。4例患者（14%）病变主要位于上叶，8例患者（28%）位于下叶，17例患者（58%）为随机分布。
AEP患者的CT表现主要包括双侧磨玻璃样密度减低区、小叶间隔增厚、支气管血管束增粗以及胸腔积液且无心脏增大。异常CT表现最常见的整体解剖分布和区域优势为随机分布。
