King M A, Pope-Harman A L, Allen J N, Christoforidis G A, Christoforidis A J
Department of Radiology, Ohio State University Hospitals, Columbus 43210, USA.
Radiology. 1997 Jun;203(3):715-9. doi: 10.1148/radiology.203.3.9169693.
To determine the radiographic and computed tomographic (CT) characteristics of acute eosinophilic pneumonia.
Twelve consecutive patients with acute eosinophilic pneumonia were included in the study. The diagnosis was based on clinical symptoms and results of bronchoalveolar lavage. Plain chest radiographs were obtained in all patients; CT scans were obtained in three patients. Two thoracic radiologists reviewed the radiographs and CT scans.
Ten patients had bilateral areas of air-space opacity on images obtained at presentation; in seven of these patients, interstitial areas of opacity were also present. Two patients had bilateral interstitial areas of opacity and no areas of air-space opacity. Interlobular septal thickening and ground-glass attenuation were present on CT scans in two patients; patchy bilateral consolidation was present on CT scans in one patient. Pleural effusion was present on radiographs in seven patients (58%) and was bilateral in five. Pleural effusion was present at some point during the course of disease in all patients. In all patients, air-space disease markedly improved within 3 days of initiation of treatment with corticosteroids.
Acute eosinophilic pneumonia should be considered as a possible diagnosis when a previously healthy person presents with acute respiratory failure of unknown origin.
确定急性嗜酸性粒细胞性肺炎的X线和计算机断层扫描（CT）特征。
本研究纳入了连续12例急性嗜酸性粒细胞性肺炎患者。诊断基于临床症状和支气管肺泡灌洗结果。所有患者均进行了胸部X线平片检查；3例患者进行了CT扫描。两名胸放射科医生对X线片和CT扫描进行了阅片。
10例患者在就诊时的影像上有双侧气腔实变区域；其中7例患者还存在间质实变区域。2例患者有双侧间质实变区域，无气腔实变区域。2例患者的CT扫描显示小叶间隔增厚和磨玻璃样衰减；1例患者的CT扫描显示双侧斑片状实变。7例患者（58%）的X线片上有胸腔积液，其中5例为双侧胸腔积液。所有患者在病程中的某个时间点均出现胸腔积液。所有患者在开始使用皮质类固醇治疗后3天内，气腔病变均明显改善。
当既往健康的人出现不明原因的急性呼吸衰竭时，应考虑急性嗜酸性粒细胞性肺炎的可能诊断。
