O'Connor Angus R, Birchall James D, O'Connor Simon R, Bessell Eric
Departments of Radiology, Nottingham City Hospital, Hucknall Road, Nottingham, UK.
Nucl Med Commun. 2007 Jul;28(7):529-31. doi: 10.1097/MNM.0b013e3281e2c861.
To assess the value of (99m)Tc-MDP bone scintigraphy in the staging of primary bone lymphoma.
Thirteen staging scintigrams of patients with biopsy proven primary bone lymphoma were reviewed. The number and location of involved sites of disease were documented in each case.
Seven out of 13 scintigrams (54%) demonstrated a single site of bone involvement. Six cases (46%) showed multifocal disease, including clinically silent weight-bearing sites.
Bone scintigraphy is a valuable tool in the staging of primary bone lymphoma. It detects multifocal involvement which alters prognosis and possibly treatment. Clinically silent involvement of weight-bearing sites may be detected allowing prophylactic treatment if required.
