Paradela Sabela, Del Pozo Jesús, Fernández-Jorge Beatriz, Lozano Jesús, Martínez-González Covadonga, Fonseca Eduardo
Department of Dermatology, Hospital Juan Canalejo, La Coruña, Spain.
J Dermatolog Treat. 2007;18(3):169-74. doi: 10.1080/09546630701335180.
Epidermal nevi are benign proliferations of epidermis. Numerous treatment modalities have been tried, but no ideal treatment is yet available.
To report our experience with CO(2) laser vaporization in the treatment of verrucous epidermal nevi, and to identify which factors could have influence in long-term results.
A total of 25 patients were treated with the CO(2) laser in the superpulsed mode, focalized at 2 W/cm(2). The patients were between 3 and 41 years old (mean: 17 years). A total of 44% of lesions were <20 cm(2), 40% measured between 20 and 100 cm(2) and 16% were >100 cm(2). The follow-up was 4-79 months (mean: 28 months). In 76% of patients, multiple treatment sessions were required.
Good results were achieved in 92% of patients with soft, flattened nevi and in only 33% patients with keratotic nevi. In addition, 87% of the latter had moderate results and 12.5% had poor results.
We conclude that the CO(2) laser in superpulsed mode is an effective and safe treatment for verrucous epidermal nevi and provides fewer recurrences than other laser therapies. We also believe that the most determining factor for the cosmetic result is thickness of the nevus.
表皮痣是表皮的良性增生。人们尝试了多种治疗方法，但尚未有理想的治疗方案。
报告我们使用二氧化碳激光汽化治疗疣状表皮痣的经验，并确定哪些因素可能影响长期疗效。
共有25例患者接受了超脉冲模式的二氧化碳激光治疗，聚焦功率为2W/cm²。患者年龄在3至41岁之间（平均17岁）。44%的皮损面积小于20cm²，40%的皮损面积在20至100cm²之间，16%的皮损面积大于100cm²。随访时间为4至79个月（平均28个月）。76%的患者需要多次治疗。
92%质地柔软、变平的痣患者取得了良好效果，而角化痣患者中只有33%取得了良好效果。此外，后者中87%的患者效果中等，12.5%的患者效果较差。
我们得出结论，超脉冲模式的二氧化碳激光是治疗疣状表皮痣的一种有效且安全的方法，与其他激光疗法相比复发率更低。我们还认为，影响美容效果的最决定性因素是痣的厚度。
