Kluger Nicolas, Dereure Olivier, Guilhou Jean-Jacques, Guillot Bernard
University of Montpellier I, Department of Dermatology, Hôpital Saint-Eloi, Montpellier, France.
J Dermatolog Treat. 2007;18(3):188-90. doi: 10.1080/09546630701258101.
Genital porokeratosis (PK) is a rare and probably underestimated subset of PK that mostly affects middle-aged men. As in other clinical variants of PK, management can be difficult. Surgery and CO(2) laser vaporization may be efficient on individual lesions but topical treatment can be considered when the elements are more scattered and/or more numerous. We report the case of a 68-year-old man with a disseminated PK following a 20-year history of lesions restricted to the genitalia for whom 3% diclofenac gel succeeded in stabilizing their evolution and achieving symptomatic relief. In conclusion, topical diclofenac could be worth considering in the management of genital PK with numerous lesions.
生殖器汗孔角化症（PK）是一种罕见且可能被低估的PK亚型，主要影响中年男性。与PK的其他临床变体一样，治疗可能具有挑战性。手术和二氧化碳激光汽化对单个皮损可能有效，但当皮损更分散和/或更多时，可考虑局部治疗。我们报告一例68岁男性，患有播散性PK，其皮损局限于生殖器已有20年病史，3%双氯芬酸凝胶成功稳定了病情发展并缓解了症状。总之，对于有大量皮损的生殖器PK，局部使用双氯芬酸可能值得考虑。
