Vlachou C, Kanelleas A I, Martin-Clavijo A, Berth-Jones J
Department of Dermatology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
J Eur Acad Dermatol Venereol. 2008 Nov;22(11):1343-5. doi: 10.1111/j.1468-3083.2008.02842.x. Epub 2008 Jun 11.
Disseminated superficial actinic porokeratosis (DSAP) is the most common of the of five clinical variants of porokeratosis. These are disorders of keratinization and the distinctive pathological feature is the cornoid lamella at the margin. DSAP usually manifests in the third or fourth decades of life with a female preponderance and with multiple lesions over sun-exposed areas. A diverse range of treatments is employed though evidence of efficacy remains largely anecdotal. We report a series of eight patients with DSAP treated with 3% diclofenac gel (Solaraze gel).
播散性浅表性光化性汗孔角化症（DSAP）是汗孔角化症五种临床变型中最常见的一种。这些是角化异常性疾病，其独特的病理特征是边缘处的鸡眼样板。DSAP通常在生命的第三个或第四个十年出现，女性居多，且在暴露于阳光的部位有多个皮损。尽管疗效证据大多是传闻，但仍采用了多种治疗方法。我们报告了一系列8例用3%双氯芬酸凝胶（索拉瑞兹凝胶）治疗的DSAP患者。
