羊耳菊化学成分的研究（二）

[Studies on the chemical constituents from Inula cappa (II)].

作者信息

Guo Qi-lei, Yang Jun-shan, Liu Jian-xun

机构信息

Institute of Medicinal Plant Development, Peking Union Medical College & Chinese Academy of Medical science, Beijing 100094, China.

出版信息

Zhong Yao Cai. 2007 Jan;30(1):35-7.

PMID:17539299

Abstract

OBJECTIVE

To study the chemical constituents of the root of Inula cappa.

METHOD

The compounds were isolated and purified by recrystallization and chromatography with silica gel column and Sephadex LH-20 column. Their structures were identified by physico-chemical properties and spectral analysis.

RESULTS

Seven compounds were isolated as scopolin (I), octacosanoic acid (II), tritriacontane (III), (2S,3S,4R,8E)-2-[(2'R)-2'-hydroxydocosanosylamino]-octadecane-1,3,4-triol(IV),(2S,3S,4R,8E)-2-[(2'R)-2'-hydroxytricosanosylamino]-octadecane-1,3,4-triol(V), (2S,3S,4R,8E)-2-[(2'R)-2'-hydroxytetracosanosylamino]-octadecane-1,3,4-triol(VI), (2S,3S,4R,8E)-2-[(2'R)-2'-hydroxypentacosanosylamino]-octadecane-1,3,4-triol(VIII), (2S,3S,4R,8E)-2-[(2'R)-2'-hydroxyhexacosanosylamino]-octadecane-1,3,4-triol(VIII).

CONCLUSION

All compounds were isolated from Inula cappa for the first time.

摘要

目的

研究羊耳菊根的化学成分。

方法

通过重结晶以及硅胶柱色谱和葡聚糖凝胶LH - 20柱色谱对化合物进行分离和纯化。通过理化性质和光谱分析鉴定其结构。

结果

分离得到7种化合物，分别为东莨菪苷（I）、二十八烷酸（II）、三十三烷（III）、(2S,3S,4R,8E)-2-[(2'R)-2'-羟基二十二烷氨基]-十八烷-1,3,4-三醇（IV）、(2S,3S,4R,8E)-2-[(2'R)-2'-羟基二十三烷氨基]-十八烷-1,3,4-三醇（V）、(2S,3S,4R,8E)-2-[(2'R)-2'-羟基二十四烷氨基]-十八烷-1,3,4-三醇（VI）、(2S,3S,4R,8E)-2-[(2'R)-2'-羟基二十五烷氨基]-十八烷-1,3,4-三醇（VII）、(2S,SS,4R,8E)-2-[(2'R)-2'-羟基二十六烷氨基]-十八烷-1,3,4-三醇（VIII）。