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早期生长与发育研究:一项前瞻性收养设计。

The early growth and development study: a prospective adoption design.

作者信息

Leve Leslie D, Neiderhiser Jenae M, Ge Xiaojia, Scaramella Laura V, Conger Rand D, Reid John B, Shaw Daniel S, Reiss David

机构信息

Oregon Social Learning Center, Eugene, Oregon 97401-4928, USA.

出版信息

Twin Res Hum Genet. 2007 Feb;10(1):84-95. doi: 10.1375/twin.10.1.84.

Abstract

The Early Growth and Development Study is a prospective adoption study of birth parents, adoptive parents, and adopted children (N=359 triads) that was initiated in 2003. The primary study aims are to examine how family processes mediate or moderate the expression of genetic influences in order to aid in the identification of specific family processes that could serve as malleable targets for intervention. Participants in the study are recruited through adoption agencies located throughout the United States, following the birth of a child. Assessments occur at 6-month intervals until the child reaches 3 years of age. Data collection includes the following primary constructs: infant and toddler temperament, social behavior, and health; birth and adoptive parent personality characteristics, psychopathology, competence, stress, and substance use; adoptive parenting and marital relations; and prenatal exposure to drugs and maternal stress. Preliminary analyses suggest the representativeness of the sample and minimal confounding effects of current trends in adoption practices, including openness and selective placement. Future plans are described.

摘要

早期生长与发育研究是一项针对亲生父母、养父母和养子女(共359个三元组)开展的前瞻性收养研究,于2003年启动。该研究的主要目的是考察家庭过程如何介导或调节基因影响的表达,以帮助识别那些可作为可塑性干预目标的特定家庭过程。研究参与者是在孩子出生后通过美国各地的收养机构招募的。评估每6个月进行一次,直至孩子年满3岁。数据收集包括以下主要内容:婴幼儿气质、社会行为和健康状况;亲生父母和养父母的人格特征、精神病理学、能力、压力和物质使用情况;收养式养育和婚姻关系;以及产前药物暴露和母亲压力。初步分析表明样本具有代表性,且收养做法当前趋势(包括开放性和选择性安置)的混杂效应极小。文中还描述了未来计划。

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