Paulin I, Aulisi L, Bianchi S, Cerrini C, Rubeca T, Scozzarro F, Tozzi D, Vallin E
Università degli Studi di Firenze, Unità Operativa Chirurgica INRCA.
Minerva Chir. 1991 Aug;46(15-16):849-54.
195 patients affected by a cystic thyroid lesion were studied by a Fine Needle Aspiration biopsy (FNAb). 42 patients were operated on account of clinical data, compressive phenomena or cytologic results suggesting a neoplasia. Out of the operated patients, 3 were affected by a carcinoma in the cystic lesion (one "pure" cystic nodule and two "mixed" ones), while three more patients with multinodular goiters showed a carcinomatous lesion in a nodule different from the cystic one. Macroscopic characteristics of the aspirated fluid (quantity and quality) didn't affect the cytologic diagnosis. Cytology was useful in the preoperative diagnosis of benign thyroid nodules (only two false positives out of 42 patients) and was diagnostic in all the three patients affected by a carcinoma in the cystic nodule.
对195例患有甲状腺囊性病变的患者进行了细针穿刺活检（FNAb）。42例患者因临床数据、压迫现象或提示肿瘤形成的细胞学结果而接受手术。在接受手术的患者中，3例在囊性病变中患有癌（1例“纯”囊性结节和2例“混合”性结节），另外3例多结节性甲状腺肿患者在与囊性结节不同的结节中出现癌性病变。吸出液的宏观特征（数量和质量）不影响细胞学诊断。细胞学检查对甲状腺良性结节的术前诊断有用（42例患者中只有2例假阳性），并且对所有3例囊性结节中患有癌的患者具有诊断价值。
