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一名13岁患者的多发性幼年性黄色肉芽肿。

Multiple juvenile xanthogranulomas in a 13-year-old.

作者信息

Redbord Kelley Pagliai, Sheth Anita P

机构信息

Department of Dermatology, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.

出版信息

Pediatr Dermatol. 2007 May-Jun;24(3):238-40. doi: 10.1111/j.1525-1470.2007.00393.x.

Abstract

A 13-year-old Caucasian girl presented with a 1(1/2) month history of multiple, asymptomatic, discrete, orange-yellow to skin-colored, dome-shaped, smooth, 3 to 6 mm papules on the arms, legs, trunk, and buttock. Pathology showed a dermal infiltrate of Touton-type giant cells, scattered lymphocytes, and macrophages. The patient was diagnosed with juvenile xanthogranuloma. We present this patient because of the uncommon presentation of multiple juvenile xanthogranulomas in a 13-year-old. Although juvenile xanthogranuloma generally occurs in infancy, it must be included in the differential diagnosis for an older child. This entity can less frequently occur in adults and typically a solitary lesion is found. Multiple juvenile xanthogranuloma is rare in older children and adults. Work-up should include a thorough review of systems, physical examination, and ophthalmology examination. Pediatricians and dermatologists should be aware that juvenile xanthogranulomas might occur in older children.

摘要

一名13岁的白人女孩,手臂、腿部、躯干和臀部出现多个无症状、孤立、橙黄色至肤色、圆顶状、光滑、3至6毫米的丘疹,病程1个半月。病理显示真皮内有图顿型巨细胞、散在淋巴细胞和巨噬细胞浸润。该患者被诊断为幼年黄色肉芽肿。我们报告该病例是因为13岁患儿出现多个幼年黄色肉芽肿的情况并不常见。虽然幼年黄色肉芽肿通常发生于婴儿期,但对于大龄儿童,它也必须列入鉴别诊断。该病症在成人中较少见,通常为单个病灶。多个幼年黄色肉芽肿在大龄儿童和成人中罕见。检查应包括全面的系统回顾、体格检查和眼科检查。儿科医生和皮肤科医生应意识到幼年黄色肉芽肿可能发生于大龄儿童。

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