Urban Katelyn, Merati Miesha, Parker Lydia, Sok Carolyn, Bains Rick
Dermatology, Lake Erie College of Osteopathic Medicine, Greensburg, USA.
Dermatology, The Parker Skin and Aesthetic Clinic, Beachwood, USA.
Cureus. 2020 Aug 2;12(8):e9516. doi: 10.7759/cureus.9516.
Juvenile xanthogranuloma (JXG) is a non-Langerhans cell histiocytosis that typically presents as a solitary lesion in infancy. Multiple lesions, especially in patients over one year of age, are rarely described in the literature. The authors report a case of a 17-year-old female who presented with multiple asymptomatic nodules and plaques. The diagnosis of xanthogranuloma was confirmed with histopathologic examination of foamy histiocytes and the characteristic Touton giant cells. The expected course of multiple JXG in older patients may differ from those presenting with a solitary lesion earlier in life.
幼年性黄色肉芽肿（JXG）是一种非朗格汉斯细胞组织细胞增生症，通常在婴儿期表现为单个病变。文献中很少描述多发损害，尤其是一岁以上患者的多发损害。作者报告了一例17岁女性患者，该患者出现多个无症状结节和斑块。通过对泡沫状组织细胞和特征性杜顿巨细胞进行组织病理学检查，确诊为黄色肉芽肿。老年患者多发JXG的预期病程可能与早年出现单个病变的患者不同。
